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ChemicalBook > Product Catalogue >Biochemical Engineering >Nucleoside drugs >Nucleotides and their analogs >3-ISOBUTYL-1-METHYLXANTHINE

3-ISOBUTYL-1-METHYLXANTHINE

3-ISOBUTYL-1-METHYLXANTHINE Structure
  • ₹4321 - ₹287685.2
  • Product name: 3-ISOBUTYL-1-METHYLXANTHINE
  • CAS: 28822-58-4
  • MF: C10H14N4O2
  • MW: 222.24
  • EINECS:249-259-3
  • MDL Number:MFCD00005584
  • Synonyms:3,7-Dihydro-1-methyl-3-(2-methy;3-isobutyl-1-methyl-1H-purine-2,6(3H,9H)-dione;3-isobutyl-1-methyl-3,9-dihydro-1H-purine-2,6-dione;3-isobutyl-1-methyl-7H-purine-2,6-dione;3-isobutyl-1-methyl-7H-purine-2,6-quinone;3-Isobutyl-1-methyxanthine;3-isobutyl-1-methyl-7H-xanthine;3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
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Brand

  • Sigma-Aldrich(India)
  • ALFA India
  • ottokemi

Package

  • 100MG
  • 250MG
  • 1gm
  • 1G
  • 5gm
  • 5G
  • 5X5G
  • ManufacturerSigma-Aldrich(India)
  • Product numberI5879
  • Product description3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder
  • Packaging100MG
  • Price₹4947.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number410957
  • Product description3-Isobutyl-1-methylxanthine - CAS 28822-58-4 - Calbiochem A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC?? = 2-50 μM).
  • Packaging250MG
  • Price₹9530.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI5879
  • Product description3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder
  • Packaging250MG
  • Price₹9829.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI7018
  • Product description3-Isobutyl-1-methylxanthine ≥99%, BioUltra
  • Packaging100MG
  • Price₹10088.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI7018
  • Product description3-Isobutyl-1-methylxanthine ≥99%, BioUltra
  • Packaging250MG
  • Price₹20102.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number410957
  • Product description3-Isobutyl-1-methylxanthine - CAS 28822-58-4 - Calbiochem A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC?? = 2-50 μM).
  • Packaging1G
  • Price₹22650
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI5879
  • Product description3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder
  • Packaging1G
  • Price₹27246.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI7018
  • Product description3-Isobutyl-1-methylxanthine ≥99%, BioUltra
  • Packaging1G
  • Price₹55835.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI5879
  • Product description3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder
  • Packaging5G
  • Price₹107427.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI5879
  • Product description3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder
  • Packaging5X5G
  • Price₹287685.2
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J64598-MC
  • Product description3-Isobutyl-1-methylxanthine
  • Packaging100mg
  • Price₹4321
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number I 0022
  • Product description3-Isobutyl-1-methylxanthine, 99%+
  • Packaging100mg
  • Price₹4473
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number I 0022
  • Product description3-Isobutyl-1-methylxanthine, 99%+
  • Packaging250mg
  • Price₹8883
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number I 0022
  • Product description3-Isobutyl-1-methylxanthine, 99%+
  • Packaging1gm
  • Price₹24606
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number I 0022
  • Product description3-Isobutyl-1-methylxanthine, 99%+
  • Packaging5gm
  • Price₹97092
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) I5879 3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder 100MG ₹4947.03 2022-06-14 Buy
Sigma-Aldrich(India) 410957 3-Isobutyl-1-methylxanthine - CAS 28822-58-4 - Calbiochem A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC?? = 2-50 μM). 250MG ₹9530.01 2022-06-14 Buy
Sigma-Aldrich(India) I5879 3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder 250MG ₹9829.1 2022-06-14 Buy
Sigma-Aldrich(India) I7018 3-Isobutyl-1-methylxanthine ≥99%, BioUltra 100MG ₹10088.9 2022-06-14 Buy
Sigma-Aldrich(India) I7018 3-Isobutyl-1-methylxanthine ≥99%, BioUltra 250MG ₹20102.03 2022-06-14 Buy
Sigma-Aldrich(India) 410957 3-Isobutyl-1-methylxanthine - CAS 28822-58-4 - Calbiochem A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC?? = 2-50 μM). 1G ₹22650 2022-06-14 Buy
Sigma-Aldrich(India) I5879 3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder 1G ₹27246.53 2022-06-14 Buy
Sigma-Aldrich(India) I7018 3-Isobutyl-1-methylxanthine ≥99%, BioUltra 1G ₹55835.35 2022-06-14 Buy
Sigma-Aldrich(India) I5879 3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder 5G ₹107427.3 2022-06-14 Buy
Sigma-Aldrich(India) I5879 3-Isobutyl-1-methylxanthine ≥99% (HPLC), powder 5X5G ₹287685.2 2022-06-14 Buy
ALFA India ALF-J64598-MC 3-Isobutyl-1-methylxanthine 100mg ₹4321 2022-05-26 Buy
ottokemi I 0022 3-Isobutyl-1-methylxanthine, 99%+ 100mg ₹4473 2022-05-26 Buy
ottokemi I 0022 3-Isobutyl-1-methylxanthine, 99%+ 250mg ₹8883 2022-05-26 Buy
ottokemi I 0022 3-Isobutyl-1-methylxanthine, 99%+ 1gm ₹24606 2022-05-26 Buy
ottokemi I 0022 3-Isobutyl-1-methylxanthine, 99%+ 5gm ₹97092 2022-05-26 Buy

Properties

Melting point :200-201 °C(lit.)
Boiling point :363.42°C (rough estimate)
Density :1.2042 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :-20°C
solubility :DMSO: 1 M with gentle warming
form :powder
pka :8.61±0.70(Predicted)
color :off-white
BRN :247859
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :APIXJSLKIYYUKG-UHFFFAOYSA-N
CAS DataBase Reference :28822-58-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.

Description

IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) (IC50 = 19, 50, 18, 13, 32, 7, and 50 μM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11, respectively). PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP levels, activating cyclic-nucleotide-regulated protein kinases. Methylxanthines, including IBMX, caffeine, and theophylline, bind adenosine receptors, typically antagonizing the suppressive effects of natural agonists.

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