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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Bulk Drug Intermediates >(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Structure
  • ₹5823.85 - ₹16172.55
  • Product name: (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
  • CAS: 291775-59-2
  • MF: C12H19NO4
  • MW: 241.28
  • EINECS:808-164-2
  • MDL Number:MFCD11099876
  • Synonyms:(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-(Tert-butoxycarbonyl)-2-azabicyclo-[2.2.1]-heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%;2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 2-(1,1-diMethylethyl) ester, (1R,3S,4S)-;(1R,3S,4S)-3-[(2-methylpropoxy)carbonyl]-2-azabicyclo[2.2.1]heptane-2-carboxylic acid;Ledipasvir INT 2;Ledipasvir Impurity 14
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 250MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product number695491
  • Product description(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%
  • Packaging250MG
  • Price₹5823.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number695491
  • Product description(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%
  • Packaging1G
  • Price₹16172.55
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 695491 (1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97% 250MG ₹5823.85 2022-06-14 Buy
Sigma-Aldrich(India) 695491 (1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97% 1G ₹16172.55 2022-06-14 Buy

Properties

Melting point :147-152 °C
Boiling point :371.0±25.0 °C(Predicted)
Density :1.232±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
pka :4.05±0.20(Predicted)
optical activity :[α]22/D -170±10°, c = 1 in chloroform
InChIKey :IFAMSTPTNRJBRG-YIZRAAEISA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

(1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-??daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants.

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Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
₹0.00 /25KG
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid CAS:291775-59-2
Henan Bao Enluo International TradeCo.，LTD
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
₹10.00/kg
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid CAS:291775-59-2
Ouhuang Engineering Materials (Hubei) Co., Ltd
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
₹5.00 /25kg
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid CAS:291775-59-2
A.J Chemicals CLEARSYNTH LABS LTD. SynZeal Research Pvt Ltd
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED