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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Proteases >HCV Protease Inhibitors >Ledipasvir

Ledipasvir

Ledipasvir Structure
  • ₹0
  • Product name: Ledipasvir
  • CAS: 1256388-51-8
  • MF: C49H54F2N8O6
  • MW: 889
  • EINECS:1592732-453-0
  • MDL Number:MFCD25976756
  • Synonyms:GS 5885;GS5885;GS-5885;Ledipasvir;GS-5885/Ledipasvir;gs-5885/gs5885;Ledipasvir / GS 5885;GS 588
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :186-190oC
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly, Heated), Methanol (Slightly)
pka :11.20±0.10(Predicted)
form :Solid
color :White to Pale Beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ledipasvir is a potent NS5A inhibitor that is approved for use in combination with sofosbuvir, a nucleotide inhibitor of viral polymerase, for the treatment of chronic hepatitis C virus genotype 1 infection. This combination was discovered and developed at Gilead Sciences and is marketed as the fixed combination with brand name of Harvoni.

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Suppliers and manufacturers

Jigs Chemical ltd Lupin Ltd VIVIN DRUGS AND PHARMACEUTICALS LTD NATCO Pharma Limited Humble Healthcare Limited Mylan Laboratories Ltd BDR Pharmaceuticals International Pvt Ltd LUPIN LTD A.J Chemicals CLEARSYNTH LABS LTD.