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3-BROMO-7-NITROINDAZOLE

3-BROMO-7-NITROINDAZOLE Structure
  • ₹0
  • Product name: 3-BROMO-7-NITROINDAZOLE
  • CAS: 74209-34-0
  • MF: C7H4BrN3O2
  • MW: 242.03
  • EINECS:
  • MDL Number:MFCD00159910
  • Synonyms:3-BroMo-7-nitro-1H-indazo...;1H-INDAZOLE,3-BROMO-7-NITRO-;BRNI;7-NITROINDAZOLE, 3-BROMO-;3-BROMO-7-NITROINDAZOLE;3-BROMO-7-NITRO-1H-INDAZOLE;3-Bromo-7-nitroindazole, 98+%;3-Bromo-7-nitroindaz
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :175-185 °C
Boiling point :182°C
Density :1.8856 (rough estimate)
refractive index :1.6200 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :ethanol: 25 mg/mL
form :powder
pka :7.85±0.40(Predicted)
color :light yellow
Sensitive :Light Sensitive
CAS DataBase Reference :74209-34-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.

Description

3-Bromo-7-nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, but unlike 7-nitroindazole, it is also potent against iNOS. The IC50 values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.17, 0.86, and 0.29 μM, respectively.

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