3-CARBETHOXYUMBELIFERONE
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- ₹10825 - ₹11400
- Product name: 3-CARBETHOXYUMBELIFERONE
- CAS: 6093-71-6
- MF: C12H10O5
- MW: 234.2
- EINECS:
- MDL Number:MFCD00017641
- Synonyms:AURORA 9226;ETHYL 3-UMBELLIFERYLCARBOXYLATE;7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID ETHYL ESTER;AKOS BBS-00008132;3-CARBETHOXYUMBELIFERONE;UMBELLIFERONE 3-CARBOXYLIC ACID ETHYL ESTER;Ethyl 7-hydroxy-2-oxo-2H-chroMene-3-carboxylate;Ethyl 7-Hydroxycoumarin-3-carboxylate
2 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 200MG
- ManufacturerTCI Chemicals (India)
- Product numberE1017
- Product descriptionEthyl 7-Hydroxycoumarin-3-carboxylate min. 98.0 %
- Packaging200MG
- Price₹11400
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1270
- Product descriptionYZ9 ≥98% (HPLC)
- Packaging10MG
- Price₹10825
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | E1017 | Ethyl 7-Hydroxycoumarin-3-carboxylate min. 98.0 % | 200MG | ₹11400 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | SML1270 | YZ9 ≥98% (HPLC) | 10MG | ₹10825 | 2022-06-14 | Buy |
Properties
Melting point :170.0 to 174.0 °C
Boiling point :448.3±45.0 °C(Predicted)
Density :1.397±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :7.32±0.20(Predicted)
form :powder
color :white to beige
λmax :398nm(EtOH)(lit.)
CAS DataBase Reference :6093-71-6
Boiling point :448.3±45.0 °C(Predicted)
Density :1.397±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :7.32±0.20(Predicted)
form :powder
color :white to beige
λmax :398nm(EtOH)(lit.)
CAS DataBase Reference :6093-71-6
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Cells that are rapidly proliferating or hypoxic emphasize glycolysis over oxidative phosphorylation to meet energy needs. During glycolysis, fructose 6-phosphate (F6P) is phosphorylated by 6-phosphofructo-2-kinases (PFKs) to generate fructose 2,6-bisphosphate. As PFK family members also mediate the reverse reaction as fructose 2,6-bisphosphatases, these enzymes are known as PFKFB family members. Notably, PFKFB3 is overexpressed in a wide variety of cancer cell lines. YZ9 is a potent inhibitor of PFKFB3, with an IC50 value of 183 nM in vitro. It avidly competes with F6P at PFKFB3 (Ki = 94 nM). YZ9 is also cell permeable, inhibiting the growth of HeLa cells with a GI50 value of 2.7 μM.Related product price
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