1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID
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- ₹0
- Product name: 1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID
- CAS: 306935-41-1
- MF: C10H11N3O2
- MW: 205.21
- EINECS:
- MDL Number:MFCD01570664
- Synonyms:BUTTPARK 36\04-50;IBC 293;IPBT-5CA;1-ISOPROPYL-1H-BENZO[D][1,2,3]TRIAZOLE-5-CARBOXYLIC ACID;1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID;1-ISOPROPYL-1H-BENZOTRIAZOLE-5-CARBOXYLIC ACID;1-ISOPROPYLBENZOTRIAZOLE-5-CARBOXYLIC ACID;1-(1-METHYLETHYL)-1H-BENZOTRIAZOLE-5-CARBOXYLIC ACID
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
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Properties
Melting point :229-230°C
Boiling point :413.9±18.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :Soluble in DMSO (up to 25 mg/ml).
form :Light brown solid
pka :3.50±0.30(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :306935-41-1(CAS DataBase Reference)
Boiling point :413.9±18.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :Soluble in DMSO (up to 25 mg/ml).
form :Light brown solid
pka :3.50±0.30(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :306935-41-1(CAS DataBase Reference)
Safety Information
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Description
The G protein-coupled receptors GPR109A and GPR109B are recognized to be receptors for hydroxy-carboxylic acid (HCA) metabolites, are abundant in adipocytes, and are relevant to atherosclerosis and dyslipidemia. IPBT-5CA is a selective agonist of GPR109B (HCA3; EC50 = 400 nM). It displays no activity at GPR109A (HCA2). IBC-293 inhibits forskolin-stimulated cAMP release in Chinese hamster ovary cells stably expressing GPR109B (EC50 = 54 nM) but not in cells expressing GPR109A. This is accompanied by a rapid and transient increase in intracellular calcium and activation of ERK1/2 through a pertussis toxin-sensitive Gi signaling pathway.More related product prices
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