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ChemicalBook > Product Catalogue >API >Antiallergic drugs >Allergic Reactions >Zafirlukast

Zafirlukast

Zafirlukast Structure
  • ₹8746.6 - ₹35841.58
  • Product name: Zafirlukast
  • CAS: 107753-78-6
  • MF: C31H33N3O6S
  • MW: 575.68
  • EINECS:
  • MDL Number:MFCD00864775
  • Synonyms:Carbamic acid, [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester;Cyclopentyl 3-[2-methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methylindole-5-carbamate;[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic acid cyclopentyl ester;4-[5-(Cyclopentyloxycarbonylamino)-1-methyl-1H-indol-3-ylmethyl]-3-methoxy-N-(2-methylphenylsulfonyl)benzamide;IC-204219;Carbamic acid, N-[3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester;cyclopentyl N-{3-[(2-Methoxy-4-{[(2-Methylbenzene)sulfonyl]carbaMoyl}phenyl)Methyl]-1-Methyl-1H-indol-5-yl}carbaMate;Cyclopentyl N-[3-{[2-Methoxy-4-[(2-Methylphenyl) sulfonylcarbaMoy
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 10MG
  • 50MG
  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberZ4152
  • Product descriptionZafirlukast ≥98% (HPLC)
  • Packaging10MG
  • Price₹8746.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberZ4152
  • Product descriptionZafirlukast ≥98% (HPLC)
  • Packaging50MG
  • Price₹35841.58
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberZ0029
  • Product descriptionZafirlukast
  • Packaging100MG
  • Price₹12400
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) Z4152 Zafirlukast ≥98% (HPLC) 10MG ₹8746.6 2022-06-14 Buy
Sigma-Aldrich(India) Z4152 Zafirlukast ≥98% (HPLC) 50MG ₹35841.58 2022-06-14 Buy
TCI Chemicals (India) Z0029 Zafirlukast 100MG ₹12400 2022-05-26 Buy

Properties

Melting point :139°C
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥28mg/mL
pka :4.94±0.10(Predicted)
form :solid
color :White or pink
Merck :14,10108
Stability :Stable for 2 years as supplied. Protect from exposure to moisture. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :107753-78-6(CAS DataBase Reference)
EPA Substance Registry System :Carbamic acid, N-[3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester (107753-78-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Zafirlukast is a potent subtype specific cysteinyl leukotriene type 1 receptor (CysLT1) antagonist; antiasthmatic. The cysteinyl-leukotrienes (CysLTs), LTC4 and LTD4, are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, augment microvascular permeability, and are vasoconstrictors of coronary arteries.

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