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ChemicalBook > Product Catalogue >Biochemical Engineering >Nucleoside drugs >Deoxynucleotides and their analogs >Zalcitabine

Zalcitabine

Zalcitabine Structure
  • ₹3150 - ₹64084
  • Product name: Zalcitabine
  • CAS: 7481-89-2
  • MF: C9H13N3O3
  • MW: 211.22
  • EINECS:620-762-3
  • MDL Number:MFCD00012188
  • Synonyms:4-AMINO-1-[(2R,5S)-5-(HYDROXYMETHYL)OXOLAN-2-YL]PYRIMIDIN-2-ONE;ZALCITABINE;1-(2',3'-DIDEOXY-BETA-RIBOFURANOSYL)CYTOSINE;2',3'-Dideoxy-D-cytidine;2'',3''-DIDEOXYCYTIDINE(ZALCITABINE);Cytidine, 2',3'-dideoxy- (8CI, 9CI);D 2C;NSC 606170
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • SRL

Package

  • 25mg
  • 100MG
  • 250MG
  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberD5782
  • Product description2′,3′-Dideoxycytidine ≥98% (HPLC)
  • Packaging100MG
  • Price₹17720.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD5782
  • Product description2′,3′-Dideoxycytidine ≥98% (HPLC)
  • Packaging250MG
  • Price₹38677.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD5782
  • Product description2′,3′-Dideoxycytidine ≥98% (HPLC)
  • Packaging500MG
  • Price₹64084
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number47248
  • Product description2,3-Dideoxycytidine (ddC) extrapure, 98%
  • Packaging25mg
  • Price₹3150
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D5782 2′,3′-Dideoxycytidine ≥98% (HPLC) 100MG ₹17720.53 2022-06-14 Buy
Sigma-Aldrich(India) D5782 2′,3′-Dideoxycytidine ≥98% (HPLC) 250MG ₹38677.73 2022-06-14 Buy
Sigma-Aldrich(India) D5782 2′,3′-Dideoxycytidine ≥98% (HPLC) 500MG ₹64084 2022-06-14 Buy
SRL 47248 2,3-Dideoxycytidine (ddC) extrapure, 98% 25mg ₹3150 2022-05-26 Buy

Properties

Melting point :217-218 °C(lit.)
Boiling point :350.9°C (rough estimate)
alpha :D25 +81° (c = 0.635 in water)
Density :1.2605 (rough estimate)
refractive index :78 ° (C=0.5, H2O)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly, Sonicated)
form :powder
pka :14.44±0.10(Predicted)
color :colorless
Water Solubility :5-10 g/100 mL at 19 ºC
Merck :14,10109
BRN :654956
Stability :Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey :WREGKURFCTUGRC-POYBYMJQSA-N
CAS DataBase Reference :7481-89-2(CAS DataBase Reference)
IARC :2B (Vol. 76) 2000
EPA Substance Registry System :Cytidine, 2',3'-dideoxy- (7481-89-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P281 Use personal protective equipment as required.

Description

Zalcitabine is an analog of pyrimidine derived from deoxycytidine with the replacement of the hydroxyl group in position 3’ with a hydrogen. In cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. Zalcitabine was the third antiretroviral approved by the FDA for treatment of HIV infection and AIDS.

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Suppliers and manufacturers

ANAXLABORATORIES PRIVATE LIMITED A.J Chemicals CLEARSYNTH LABS LTD. Sisco Research Laboratories Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd Triveni chemicals Indogulf Group Euroasia Trans Continental Anand Agencies ARCHERCHEM