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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Antimetabolites, Antineoplastic >Cytarabine

Cytarabine

Cytarabine Structure
  • ₹1150 - ₹75244.58
  • Product name: Cytarabine
  • CAS: 147-94-4
  • MF: C9H13N3O5
  • MW: 243.22
  • EINECS:205-705-9
  • MDL Number:MFCD00066487
  • Synonyms:cytrarabine;Cytosine β-D-arabinofuranoside ,98%;DEPOCYT (cytarabine);4-aMino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2-dihydropyriMidin-2-one;4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone Arabinocytidine Cytosine beta-D-Arabinofuranoside Ara-C;Cytarabine for Injection;Ara-cell;1-beta-d-arabinosylcytosine
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL

Package

  • 100MG
  • 500MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberC2035
  • Product descriptionCytarabine
  • Packaging1G
  • Price₹4300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2035
  • Product descriptionCytarabine
  • Packaging5G
  • Price₹10600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1768
  • Product descriptionCytosine β-D-arabinofuranoside crystalline, ≥90% (HPLC)
  • Packaging100MG
  • Price₹4730.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number251010
  • Product description1-β-D-Arabinofuranosylcytosine - CAS 147-94-4 - Calbiochem Anticancer, antiviral agent that is especially effective against leukemias.
  • Packaging1G
  • Price₹11730
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1768
  • Product descriptionCytosine β-D-arabinofuranoside crystalline, ≥90% (HPLC)
  • Packaging500MG
  • Price₹15642.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1787
  • Product descriptionCytarabine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹16053.48
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1768
  • Product descriptionCytosine β-D-arabinofuranoside crystalline, ≥90% (HPLC)
  • Packaging1G
  • Price₹21790.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1768
  • Product descriptionCytosine β-D-arabinofuranoside crystalline, ≥90% (HPLC)
  • Packaging5G
  • Price₹75244.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number62682
  • Product descriptionCytosine Arabinoside extrapure, 98%
  • Packaging100mg
  • Price₹1150
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number62682
  • Product descriptionCytosine Arabinoside extrapure, 98%
  • Packaging500mg
  • Price₹3630
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C2035 Cytarabine 1G ₹4300 2022-05-26 Buy
TCI Chemicals (India) C2035 Cytarabine 5G ₹10600 2022-05-26 Buy
Sigma-Aldrich(India) C1768 Cytosine β-D-arabinofuranoside crystalline, ≥90% (HPLC) 100MG ₹4730.53 2022-06-14 Buy
Sigma-Aldrich(India) 251010 1-β-D-Arabinofuranosylcytosine - CAS 147-94-4 - Calbiochem Anticancer, antiviral agent that is especially effective against leukemias. 1G ₹11730 2022-06-14 Buy
Sigma-Aldrich(India) C1768 Cytosine β-D-arabinofuranoside crystalline, ≥90% (HPLC) 500MG ₹15642.13 2022-06-14 Buy
Sigma-Aldrich(India) PHR1787 Cytarabine Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹16053.48 2022-06-14 Buy
Sigma-Aldrich(India) C1768 Cytosine β-D-arabinofuranoside crystalline, ≥90% (HPLC) 1G ₹21790.73 2022-06-14 Buy
Sigma-Aldrich(India) C1768 Cytosine β-D-arabinofuranoside crystalline, ≥90% (HPLC) 5G ₹75244.58 2022-06-14 Buy
SRL 62682 Cytosine Arabinoside extrapure, 98% 100mg ₹1150 2022-05-26 Buy
SRL 62682 Cytosine Arabinoside extrapure, 98% 500mg ₹3630 2022-05-26 Buy

Properties

Melting point :214 °C
alpha :D24 +153° (c = 0.5 in water)
Boiling point :386.09°C (rough estimate)
Density :1.3686 (rough estimate)
refractive index :1.5100 (estimate)
storage temp. :2-8°C
solubility :H2O: 50 mg/mL, clear, colorless
form :crystalline
pka :pKa 4.3 (Uncertain)
color :Prisms from EtOH (aq)
Water Solubility :almost transparency
λmax :272nm(H2O)(lit.)
Merck :14,2784
BRN :89175
Stability :Stable for 1 year as supplied from date of purchase. Solutions in DMSO or water may be stored at -20°C for up to 1 month.
InChIKey :UHDGCWIWMRVCDJ-STUHELBRSA-N
LogP :-1.808 (est)
CAS DataBase Reference :147-94-4(CAS DataBase Reference)
EPA Substance Registry System :Cytarabine (147-94-4)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Cytarabine is a nucleoside analog that differs from cytosine by the presence of a hydroxyl group at the 2’ position of the sugar residue. It is triphosphorylated in vivo to produce ara-CTP, a competitive inhibitor of DNA polymerases α and β (Kis = 4 and 32 μM, respectively). At low concentrations, ara-CTP is incorporated into DNA, slowing but not stopping DNA synthesis. Cytarabine is effective in the treatment of leukemias. It can also have antiviral actions on certain types of viruses.

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