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Enocitabine

Enocitabine Structure
  • ₹0
  • Product name: Enocitabine
  • CAS: 55726-47-1
  • MF: C31H55N3O6
  • MW: 565.78
  • EINECS:1312995-182-4
  • MDL Number:MFCD00866294
  • Synonyms:N-(1-BETA-D-ARABINOFURANOSYL-1,2-DIHYDRO-2-OXO-4-PYRIMIDINYL)DOCOSANAMIDE;NSC-239336;SUNRABIN;BEHENOYLCYTOSINE ARABINOSIDE;BH-AC;ENOCITABINE;n-(1-beta-d-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-docosanamid ;n(sup4)-behenoyl-1-beta-d-arabinofuranosylcytosine
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Properties

Melting point :141-142°C
alpha :D +70° (c = 1 in THF, 22°)
Boiling point :630.87°C (rough estimate)
Density :1.0967 (rough estimate)
refractive index :1.7800 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly, Heated), THF (Slightly, Heated, Soncited)
pka :10.14±0.20(Predicted)
form :Solid
color :White to Off-White
CAS DataBase Reference :55726-47-1(CAS DataBase Reference)

Safety Information

Symbol(GHS):
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Enocitabine (NSC-239336, BHAC) is an antileukemic agent closely related to cytarabine. It appears more resistant to deamination than cytarabine, thus allowing greater in vivo phosphorylation into an active cytotoxic metabolite. Enocitabine is lipophilic, but the drug does not enter the cerebrospinal fluid and is concentrated in the bone marrow and red blood cells. It can be administered orally and appears to be more effective than the parent compound in preclinical models.

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