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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Sulfonates / Sulfinates salts >Phenylmethylsulfonyl fluoride

Phenylmethylsulfonyl fluoride

Phenylmethylsulfonyl fluoride Structure
  • ₹513 - ₹192520
  • Product name: Phenylmethylsulfonyl fluoride
  • CAS: 329-98-6
  • MF: C7H7FO2S
  • MW: 174.19
  • EINECS:206-350-2
  • MDL Number:MFCD00007424
  • Synonyms:α-toluenesulphonyl fluoride;Phenylmethanesulfonyl fluoride,α-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, PMSF, Phenylmethylsulfonyl fluoride;Phenylmethanesulfony;BENZYLSULFONYL FLUORIDE;A-TOLUENESULFONYL FLUORIDE;A-TOLUENESULPHONYL FLUORIDE;BENZENEMETHANESULFONYL FLUORIDE;P-TOLUENESULPHONYL FLUORIDE
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL
  • ottokemi

Package

  • 250MG
  • 1gm
  • 1G
  • 5gm
  • 5G
  • 25gm
  • 25G
  • 50ML
  • 100G
  • 100gm
  • 250G
  • 250ML
  • 1Gms
  • 5Gms
  • 25Gms
  • ManufacturerTCI Chemicals (India)
  • Product numberB1062
  • Product descriptionBenzylsulfonyl Fluoride min. 98.0 %
  • Packaging5G
  • Price₹3700
  • Updated2022-05-26
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  • ManufacturerTCI Chemicals (India)
  • Product numberB3473
  • Product descriptionBenzylsulfonyl Fluoride [for Biochemical Research] min. 98.0 %
  • Packaging5G
  • Price₹6300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB1062
  • Product descriptionBenzylsulfonyl Fluoride min. 98.0 %
  • Packaging25G
  • Price₹8000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3473
  • Product descriptionBenzylsulfonyl Fluoride [for Biochemical Research] min. 98.0 %
  • Packaging25G
  • Price₹15200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7626
  • Product descriptionPhenylmethanesulfonyl fluoride ≥98.5% (GC)
  • Packaging250MG
  • Price₹2321
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberP7626
  • Product descriptionPhenylmethanesulfonyl fluoride ≥98.5% (GC)
  • Packaging1G
  • Price₹2479.25
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number52332
  • Product descriptionPhenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine resid
  • Packaging1G
  • Price₹5990.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number93482
  • Product descriptionPhenylmethanesulfonyl fluoride solution ~0.1?M in ethanol (T)
  • Packaging50ML
  • Price₹6171.2
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number78830
  • Product descriptionPhenylmethanesulfonyl fluoride ≥99.0% (T)
  • Packaging1G
  • Price₹6361.65
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number7110-OP
  • Product descriptionOmniPur® Phenylmethyl Sulfonyl Fluoride
  • Packaging5G
  • Price₹6410
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number78830
  • Product descriptionPhenylmethanesulfonyl fluoride ≥99.0% (T)
  • Packaging25G
  • Price₹32810.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7626
  • Product descriptionPhenylmethanesulfonyl fluoride ≥98.5% (GC)
  • Packaging100G
  • Price₹87818.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number7110-OP
  • Product descriptionOmniPur® Phenylmethyl Sulfonyl Fluoride
  • Packaging250G
  • Price₹192520
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7626
  • Product descriptionPhenylmethanesulfonyl fluoride ≥98.5% (GC)
  • Packaging5G
  • Price₹6572.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number78830
  • Product descriptionPhenylmethanesulfonyl fluoride ≥99.0% (T)
  • Packaging5G
  • Price₹8345.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number52332
  • Product descriptionPhenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine resid
  • Packaging5G
  • Price₹9389.99
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B1062 Benzylsulfonyl Fluoride min. 98.0 % 5G ₹3700 2022-05-26 Buy
TCI Chemicals (India) B3473 Benzylsulfonyl Fluoride [for Biochemical Research] min. 98.0 % 5G ₹6300 2022-05-26 Buy
TCI Chemicals (India) B1062 Benzylsulfonyl Fluoride min. 98.0 % 25G ₹8000 2022-05-26 Buy
TCI Chemicals (India) B3473 Benzylsulfonyl Fluoride [for Biochemical Research] min. 98.0 % 25G ₹15200 2022-05-26 Buy
Sigma-Aldrich(India) P7626 Phenylmethanesulfonyl fluoride ≥98.5% (GC) 250MG ₹2321 2022-06-14 Buy
Sigma-Aldrich(India) P7626 Phenylmethanesulfonyl fluoride ≥98.5% (GC) 1G ₹2479.25 2022-06-14 Buy
Sigma-Aldrich(India) 52332 Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine resid 1G ₹5990.01 2022-06-14 Buy
Sigma-Aldrich(India) 93482 Phenylmethanesulfonyl fluoride solution ~0.1?M in ethanol (T) 50ML ₹6171.2 2022-06-14 Buy
Sigma-Aldrich(India) 78830 Phenylmethanesulfonyl fluoride ≥99.0% (T) 1G ₹6361.65 2022-06-14 Buy
Sigma-Aldrich(India) 7110-OP OmniPur® Phenylmethyl Sulfonyl Fluoride 5G ₹6410 2022-06-14 Buy
Sigma-Aldrich(India) 78830 Phenylmethanesulfonyl fluoride ≥99.0% (T) 25G ₹32810.5 2022-06-14 Buy
Sigma-Aldrich(India) P7626 Phenylmethanesulfonyl fluoride ≥98.5% (GC) 100G ₹87818.2 2022-06-14 Buy
Sigma-Aldrich(India) 7110-OP OmniPur® Phenylmethyl Sulfonyl Fluoride 250G ₹192520 2022-06-14 Buy
Sigma-Aldrich(India) P7626 Phenylmethanesulfonyl fluoride ≥98.5% (GC) 5G ₹6572.65 2022-06-14 Buy
Sigma-Aldrich(India) 78830 Phenylmethanesulfonyl fluoride ≥99.0% (T) 5G ₹8345.05 2022-06-14 Buy
Sigma-Aldrich(India) 52332 Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine resid 5G ₹9389.99 2022-06-14 Buy

Properties

Melting point :92-95 °C
Boiling point :112 °C16 mm Hg(lit.)
Density :0.797 g/mL at 20 °C
Flash point :222 °F
storage temp. :2-8°C
solubility :dry solvents (ethanol, methanol, and 2-propanol): 200 mM Stock solution are stable for months at 4°C.
form :Needles (May Agglomerate)
color :White
Water Solubility :hydrolysis
Sensitive :Moisture Sensitive
Merck :14,7542
BRN :2088311
Stability :Moisture Sensitive
InChIKey :YBYRMVIVWMBXKQ-UHFFFAOYSA-N
CAS DataBase Reference :329-98-6(CAS DataBase Reference)
EPA Substance Registry System :Benzenemethanesulfonyl fluoride (329-98-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phenylmethylsulfonyl fluoride (PMSF) is a nonspecific, irreversible inhibitor of serine proteases and other enzymes, including acetylcholinesterase, palmityl coenzyme A deacylase, arylsulfatase A, chymotrypsin, and trypsin. It is used in protein solublization studies in order to deactivate proteases from digesting proteins of interest after cell lysis. Because PMSF specifically sulfonylates the hydroxal groups of active site serine residues of enzymes, it can be used as a chemical label to identify essential active site serines in an enzyme. PMSF is known to alter the actions of anandamide by blocking its metabolism and can produce cannabinoid effects in mice, including antinociception, hypothermia, and immobility with ED50 values of 86, 224, and 206 mg/kg, respectively.

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