Vardenafil hydrochloride trihydrate
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- ₹22700.03
- Product name: Vardenafil hydrochloride trihydrate
- CAS: 330808-88-3
- MF: C23H35ClN6O5S
- MW: 543.08
- EINECS:
- MDL Number:MFCD08458876
- Synonyms:IMidazo[5,1-f][1,2,4]triazin-4(1H)-one,2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-Methyl-7-propyl-,hydrochloride, hydrate (1:1:3);Vardenafil for system suitability;Verdenafil Hydrochloride Trihydrate;Vardenafil hydrochloride CRS;2-(2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride trihydrate;vardenafil hydrochloride trihyrate;Vardenafil Hydrochloride TrihydrateQ: What is Vardenafil Hydrochloride Trihydrate Q: What is the CAS Number of Vardenafil Hydrochloride Trihydrate Q: What is the storage condition of Vardenafil Hydrochloride Trihydrate;Vardenafil Hydrochloride (1711010)
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Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 500MG
- ManufacturerSigma-Aldrich(India)
- Product numberPHR2720
- Product descriptionVardenafil Hydrochloride certified reference material, pharmaceutical secondary standard
- Packaging500MG
- Price₹22700.03
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR2720 | Vardenafil Hydrochloride certified reference material, pharmaceutical secondary standard | 500MG | ₹22700.03 | 2022-06-14 | Buy |
Properties
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :≥13.3 mg/mL in DMSO; ≥3.42 mg/mL in EtOH with gentle warming and ultrasonic; ≥95 mg/mL in H2O
form :Solid
color :White to off-white
solubility :≥13.3 mg/mL in DMSO; ≥3.42 mg/mL in EtOH with gentle warming and ultrasonic; ≥95 mg/mL in H2O
form :Solid
color :White to off-white
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Description
Selective inhibitors of phosphodiesterase 5 (PDE5), which specifically hydrolyzes cGMP, are used to study signaling through the guanylate cyclase activator nitric oxide and to mediate smooth muscle relaxation and vasodilation triggered by cGMP. Vardenafil is a potent inhibitor of PDE5 (IC50 = 0.2-1.2 nM) that less effectively blocks the activities of PDE6, PDE1, and PDE11 (IC50s = 2, 230, and 130 nM, respectively). PDE5 inhibitors, including vardenafil, have applications in several conditions, including erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.Related product price
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