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ChemicalBook > Product Catalogue >API >Anesthetic Agents >General anesthetics >(S)-(+)-Ketamine hydrochloride

(S)-(+)-Ketamine hydrochloride

(S)-(+)-Ketamine hydrochloride Structure
  • ₹0
  • Product name: (S)-(+)-Ketamine hydrochloride
  • CAS: 33795-24-3
  • MF: C13H17Cl2NO
  • MW: 274.19
  • EINECS:625-831-1
  • MDL Number:MFCD00051420
  • Synonyms:2-(2-CHLOROPHENYL)-2-(METHYLAMINO)-CYCLOHEXANONE HCL;2-(2-CHLOROPHENYL)-2-(METHYLAMINO)CYCLOHEXANONE HYDROCHLORIDE;KETAMINE HCL;(-)-(R)-Ketamine hydrochloride;(R)-(+)-Ketamine hydrochloride;Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, hydrochloride, (2R)- (9CI);Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, hydrochloride, (R)-;Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, hydrochloride, (+)- (8CI)
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

storage temp. :2-8°C
solubility :H2O: 200 mg/mL
form :solid
color :white
CAS DataBase Reference :33795-24-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

The receptor for NMDA is a glutamate-gated ion channel that has key roles in synaptic plasticity, memory acquisition, hyperalgesia, and allodynia. Ketamine is an NMDA receptor channel blocker (Ki = 1.2-2.5 μM, IC50 = 3.2-6.1 μM). (R)-Ketamine is about 4 times less potent as an analgesic than the S-enantiomer. It is a dissociative anesthetic that has analgesic properties at subanesthetic doses. Ketamine and its analog methoxetamine are abused recreationally. Ketamine is regulated as a Schedule III compound in the United States. This product is intended for forensic and research purposes.

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