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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Quinoline compounds >4-chloro-6,7-dimethoxyquinoline

4-chloro-6,7-dimethoxyquinoline

4-chloro-6,7-dimethoxyquinoline Structure
  • ₹9017.23 - ₹28200
  • Product name: 4-chloro-6,7-dimethoxyquinoline
  • CAS: 35654-56-9
  • MF: C11H10ClNO2
  • MW: 223.66
  • EINECS:676-028-8
  • MDL Number:MFCD07778437
  • Synonyms:6,7-DIMETHOXY-4-CHLOROQUINOLINE;4-CHLORO-6,7-DIMETHOXYQUINOLINE;Quinoline, 4-chloro-6,7-dimethoxy-;4-CHLORO-6,7-DIMETHOXYQUINOLINE(35654-56-9);Cabozantinib 4-Chloroquinoline Impurity;4-Chloro-6,7-dimethoxyquinoline >oro-6,7-dimethoxyquinoL;Cabozantinib Impurity 71
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 250MG
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberC2938
  • Product description4-Chloro-6,7-dimethoxyquinoline min. 98.0 %
  • Packaging5G
  • Price₹10000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2938
  • Product description4-Chloro-6,7-dimethoxyquinoline min. 98.0 %
  • Packaging25G
  • Price₹28200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberCDS007782
  • Product description4-chloro-6,7-dimethoxyquinoline AldrichCPR
  • Packaging250MG
  • Price₹9017.23
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C2938 4-Chloro-6,7-dimethoxyquinoline min. 98.0 % 5G ₹10000 2022-05-26 Buy
TCI Chemicals (India) C2938 4-Chloro-6,7-dimethoxyquinoline min. 98.0 % 25G ₹28200 2022-05-26 Buy
Sigma-Aldrich(India) CDS007782 4-chloro-6,7-dimethoxyquinoline AldrichCPR 250MG ₹9017.23 2022-06-14 Buy

Properties

Melting point :132.0 to 136.0 °C
Boiling point :325.2±37.0 °C(Predicted)
Density :1.265±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :3.95±0.30(Predicted)
color :Pale Brown to Light Brown
InChI :InChI=1S/C11H10ClNO2/c1-14-10-5-7-8(12)3-4-13-9(7)6-11(10)15-2/h3-6H,1-2H3
InChIKey :WRVHQEYBCDPZEU-UHFFFAOYSA-N
SMILES :N1C2C(=CC(OC)=C(OC)C=2)C(Cl)=CC=1
CAS DataBase Reference :35654-56-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

4-Chloro-6,7-dimethoxyquinoline, can be used as an intermediate for the synthesis of various pharmaceutical and biologically active compounds. It is used for the preparation of Tivozanib (T447205), and Cabozantinib (C051500), acting as anticancer agents.

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