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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >DNA damage >DNA / RNA Synthesis inhibitors >Procarbazine hydrochloride

Procarbazine hydrochloride

Procarbazine hydrochloride Structure
  • ₹3200 - ₹38829.28
  • Product name: Procarbazine hydrochloride
  • CAS: 366-70-1
  • MF: C12H20ClN3O
  • MW: 257.76
  • EINECS:206-678-6
  • MDL Number:MFCD00072082
  • Synonyms:N-(1-methylethyl)-4-[(2-methylhydrazinyl)methyl]-benzamide,hydrochloride (1:1);NSC-77213 HCl;N-(1-Methylethyl)-4-[(2-methylhydrazinyl)methyl]benzamide hydrochloride;Procarbazine hydrochloride, >=99%;Procarbazine hydrochloride (Matulane);ibenzmethyzinhydrochloride ;ibz ;n-(1-methylethyl)-4-((2-methylhydrazino)methyl)-benzamidmonohydrochlorid
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 100MG
  • 500MG
  • ManufacturerTCI Chemicals (India)
  • Product numberP2550
  • Product descriptionProcarbazine Hydrochloride
  • Packaging100MG
  • Price₹3200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP2550
  • Product descriptionProcarbazine Hydrochloride
  • Packaging500MG
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0036
  • Product descriptionProcarbazine hydrochloride ≥98% (HPLC)
  • Packaging10MG
  • Price₹9601.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0036
  • Product descriptionProcarbazine hydrochloride ≥98% (HPLC)
  • Packaging50MG
  • Price₹38829.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P2550 Procarbazine Hydrochloride 100MG ₹3200 2022-05-26 Buy
TCI Chemicals (India) P2550 Procarbazine Hydrochloride 500MG ₹9800 2022-05-26 Buy
Sigma-Aldrich(India) SML0036 Procarbazine hydrochloride ≥98% (HPLC) 10MG ₹9601.78 2022-06-14 Buy
Sigma-Aldrich(India) SML0036 Procarbazine hydrochloride ≥98% (HPLC) 50MG ₹38829.28 2022-06-14 Buy

Properties

Melting point :223°C
Density :8.3 g/cm3
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: ≥18mg/mL
form :powder
color :white to tan
Water Solubility :>=10 g/100 mL at 21.5 ºC
Merck :14,7758
BCS Class :3/1
CAS DataBase Reference :366-70-1(CAS DataBase Reference)
IARC :2A (Vol. 26, Sup 7) 1987
EPA Substance Registry System :Procarbazine hydrochloride (366-70-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Procarbazine is a methyl hydrazine derivative that is converted by metabolism into a methylating species which converts DNA to various DNA adducts, including O6-methylguanine. While this process is mutagenic and carcinogenic, procarbazine is used with the compounds mechlorethamine, vincristine, also known as oncovin , and prednisone as part of the MOPP regimen for fighting Hodgkin disease. Procarbazine also has utility, in combination with other agents, in reducing the frequency of epileptic seizures in patients with pharmacoresistant epilepsy.

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Suppliers and manufacturers

Shaanxi Dideu Medichem Co. Ltd
Procarbazine hydrochloride
₹1.00 /1KG
Procarbazine hydrochloride CAS:366-70-1
Hebei Mojin Biotechnology Co., Ltd
Procarbazine hydrochloride
₹0.00 /25KG
Procarbazine hydrochloride CAS:366-70-1
Henan Bao Enluo International TradeCo.，LTD
Procarbazine hydrochloride
₹50.00 /1kg
Procarbazine hydrochloride CAS:366-70-1
Surajlok Chemicals Pvt Ltd (Neon Laboratories Ltd) MYLAN API US LLC CLEARSYNTH LABS LTD. TCI Chemicals (India) Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd K. R. Mehta And Co. Manus Aktteva