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3-AMINO-1H-PYRAZOLO[3,4-B]QUINOXALINE

3-AMINO-1H-PYRAZOLO[3,4-B]QUINOXALINE Structure
  • ₹20250
  • Product name: 3-AMINO-1H-PYRAZOLO[3,4-B]QUINOXALINE
  • CAS: 40254-90-8
  • MF: C9H7N5
  • MW: 185.19
  • EINECS:
  • MDL Number:MFCD04038461
  • Synonyms:1H-PYRAZOLO[3,4-B]QUINOXALIN-3-AMINE;3-AMINO-1H-PYRAZOLO[3,4-B]QUINOXALINE;NSC 693868;1H-Pyrazolo[3,4-b]quinoxalin-3-amine(9CI);3-Aminopyrazolo[3,4-b]quinoxaline;1H-Pyrazolo[3,4-b]quinoxalin-3-ylamine;Cdk1/5 Inhibitor - CAS 40254-90-8 - Calbiochem;Brimonidine Impurity 8
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number217720
  • Product descriptionCdk1/5 Inhibitor - CAS 40254-90-8 - Calbiochem The Cdk1/5 Inhibitor, also referenced under CAS 40254-90-8, controls the biological activity of Cdk1/5. This small molecule/inhibitor is primarily use
  • Packaging5MG
  • Price₹20250
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 217720 Cdk1/5 Inhibitor - CAS 40254-90-8 - Calbiochem The Cdk1/5 Inhibitor, also referenced under CAS 40254-90-8, controls the biological activity of Cdk1/5. This small molecule/inhibitor is primarily use 5MG ₹20250 2022-06-14 Buy

Properties

Melting point :292-293℃ (ethanol )
Boiling point :522.8±45.0 °C(Predicted)
Density :1.570±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Soluble to 100 mM in DMSO
form :Red solid
pka :7.40±0.50(Predicted)
color :Orange to red

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/5 Inhibitor is a pyrazolo [3,4-b] quioxaline that inhibits Cdk1/cyclin B and Cdk5/p25 (IC50s = 600 and 400 nM, respectively). It less potently inhibits GSK3β (IC50 = 1 μM) and does not block Cdc25 activity. This compound is used to help define the roles of Cdk1 and Cdk5 in various signaling pathways.

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