N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE
![N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE Structure](/CAS/GIF/405098-33-1.gif)
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- ₹16670.01 - ₹51390
- Product name: N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE
- CAS: 405098-33-1
- MF: C30H37ClN2O2
- MW: 493.08
- EINECS:
- MDL Number:MFCD26142284
- Synonyms:N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE;N-{[4-(diMethylaMino)phenyl]Methyl}-7-Methoxy-N-[4-(propan-2-yl)phenyl]-1,2,3,4-tetrahydronaphthalene-1-carboxaMide hydrochloride;W-54011;C5a Receptor Antagonist, W-54011;CS-2062;chemotaxis,inhibit,orally,W-54011,mobilization,anaphylatoxin,ROS,Reactive Oxygen Species,Ca2+,C5a,neutrophils,Inhibitor,Complement System,W54011,inflammatory,W 54011;W-54011, 10 mM in DMSO
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- Sigma-Aldrich
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich
- Product number234415
- Product descriptionC5a Receptor Antagonist, W-54011 - CAS 405098-33-1 - Calbiochem The C5a Receptor Antagonist, W-54011, also referenced under CAS 405098-33-1, controls the biological activity of C5a Receptor.
- Packaging1MG
- Price₹16670.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich
- Product number234415
- Product descriptionC5a Receptor Antagonist, W-54011 - CAS 405098-33-1 - Calbiochem The C5a Receptor Antagonist, W-54011, also referenced under CAS 405098-33-1, controls the biological activity of C5a Receptor.
- Packaging5MG
- Price₹51390
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number234415
- Product descriptionC5a Receptor Antagonist, W-54011 - CAS 405098-33-1 - Calbiochem The C5a Receptor Antagonist, W-54011, also referenced under CAS 405098-33-1, controls the biological activity of C5a Receptor.
- Packaging1MG
- Price₹16670.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number234415
- Product descriptionC5a Receptor Antagonist, W-54011 - CAS 405098-33-1 - Calbiochem The C5a Receptor Antagonist, W-54011, also referenced under CAS 405098-33-1, controls the biological activity of C5a Receptor.
- Packaging5MG
- Price₹51390
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich | 234415 | C5a Receptor Antagonist, W-54011 - CAS 405098-33-1 - Calbiochem The C5a Receptor Antagonist, W-54011, also referenced under CAS 405098-33-1, controls the biological activity of C5a Receptor. | 1MG | ₹16670.01 | 2022-06-14 | Buy |
| Sigma-Aldrich | 234415 | C5a Receptor Antagonist, W-54011 - CAS 405098-33-1 - Calbiochem The C5a Receptor Antagonist, W-54011, also referenced under CAS 405098-33-1, controls the biological activity of C5a Receptor. | 5MG | ₹51390 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 234415 | C5a Receptor Antagonist, W-54011 - CAS 405098-33-1 - Calbiochem The C5a Receptor Antagonist, W-54011, also referenced under CAS 405098-33-1, controls the biological activity of C5a Receptor. | 1MG | ₹16670.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 234415 | C5a Receptor Antagonist, W-54011 - CAS 405098-33-1 - Calbiochem The C5a Receptor Antagonist, W-54011, also referenced under CAS 405098-33-1, controls the biological activity of C5a Receptor. | 5MG | ₹51390 | 2022-06-14 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 3 mg/mL
form :White powder solid.
color :White to light yellow
Stability :Hygroscopic
solubility :DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 3 mg/mL
form :White powder solid.
color :White to light yellow
Stability :Hygroscopic
Safety Information
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Description
C5a Receptor Antagonist, W-54011 is a potent, specific, and orally active CD88 (C5a receptor) antagonist. Shown to inhibit the binding of 125I-rhC5a to human neutrophils with a Ki of 2.2 nM, as well as C5a-induced intracellular Ca2+-mobilization, chemotaxis and reactive oxygen species (ROS) generation (IC50 = 3.1 nM, 2.7 nM and 1.6 nM, respectively) with no agonist activity up to 10 μM. Shown to prevent C5a-induced neutrophenia in gerbils (100 μg/kg i.v. or 3-30 mg/kg orally).Related product price
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₹8584.23-28900 - W-5 HYDROCHLORIDE
₹1900-34737.43 - N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE
₹16670.01-51390
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