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2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide

2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide Structure
  • ₹13552.9 - ₹51884.23
  • Product name: 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
  • CAS: 442633-00-3
  • MF: C18H17FN2O
  • MW: 296.34
  • EINECS:
  • MDL Number:MFCD03036271
  • Synonyms:2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide;CK 666;CK-0944666;Arp2/3 Complex Inhibitor I, CK-666 ;CK 666 (CK 0944666);Benzamide, 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]-;Inhibitor,HIV,meshwork,CK-666,Actin-related protein 2/3 complex,allosteric,CK 666,state,effector,active,inhibit,CK666,trabecular,Human immunodeficiency virus,Arp2/3 Complex;CK 666, Actin polymerization inhibitor
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0006
  • Product descriptionCK-666 ≥98% (HPLC), powder
  • Packaging25MG
  • Price₹51884.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number182515
  • Product descriptionArp2/3 Complex Inhibitor I, CK-666 - CAS 442633-00-3 - Calbiochem Arp2/3 Complex Inhibitor I, CK-666, CAS 442633-00-3, is a cell-permeable selective inhibitor of actin assembly mediated by actin-related protein Arp2/
  • Packaging25MG
  • Price₹20000
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0006
  • Product descriptionCK-666 ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹13552.9
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0006 CK-666 ≥98% (HPLC), powder 25MG ₹51884.23 2022-06-14 Buy
Sigma-Aldrich(India) 182515 Arp2/3 Complex Inhibitor I, CK-666 - CAS 442633-00-3 - Calbiochem Arp2/3 Complex Inhibitor I, CK-666, CAS 442633-00-3, is a cell-permeable selective inhibitor of actin assembly mediated by actin-related protein Arp2/ 25MG ₹20000 2022-06-14 Buy
Sigma-Aldrich(India) SML0006 CK-666 ≥98% (HPLC), powder 5MG ₹13552.9 2022-06-14 Buy

Properties

Boiling point :528.2±50.0 °C(Predicted)
Density :1.235±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥25mg/mL
pka :13.86±0.46(Predicted)
form :powder
color :white to tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CK-666 (442633-00-3) is a potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50?= 4 μM for human ARP2/3.1?Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process.2 CK-666 attenuates BBB dysfunction induced by methamphetamine.3?It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal4 and pathophysiology5.

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Aladdin Scientific Shanghai Aladdin Biochemical Technology Co.,Ltd. Jinan Jiuli Biotechnology Co. , Ltd. Henan Alpha Chemical Co., Ltd. Shanghai EFE Biological Technology Co., Ltd. TargetMol Chemicals Inc.