Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
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- ₹0
- Product name: Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
- CAS: 486460-00-8
- MF: C15H18F3NO4
- MW: 333.31
- EINECS:691-120-8
- MDL Number:MFCD06659147
- Synonyms:Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,(bR)-;(R)-Sitagliptin N-Boc-Acid IMpurity;Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid;Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid, >=99%;(3R)-N-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid;(3R)-N-(tert-Butoxycarbonyl)-3-aMino-4-(2,4,5-trifluorophenyl)-butanoic acid- Boc-(R)-3-AMino-4-(2,4,5-trifluorophenyl) butanoic acid (BOC acid);[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-(R)-benzenebuta;BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID
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Properties
Melting point :136-138℃
Boiling point :443.1±45.0 °C(Predicted)
Density :1.292±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
pka :4.30±0.10(Predicted)
color :White to Off-White
Boiling point :443.1±45.0 °C(Predicted)
Density :1.292±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
pka :4.30±0.10(Predicted)
color :White to Off-White
Safety Information
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Description
Boc-(R) -3-amino-4 -(2,4, 5-trifluorophenyl) butyric acid is an important intermediate for the preparation of sitagliptin. Sitagliptinphosphate is the first dipeptidase -IV(dpp-4) inhibitor approved by FDA in 2006. It is used for the treatment of type II diabetes mellitus. It has obvious hypoglycemic effect when used alone or in combination with metformin and pioglitazone, and it is safe to take, well tolerated, with few adverse reactions.More related product prices
ETHYLENE OXIDE Butyraldehyde Sebacic acid 2-Deoxy-L-ribose BOC-(R)-3-AMINO-4-(2-FLUORO-PHENYL)-BUTYRIC ACID BOC-(R)-3-AMINO-4-(3,4-DIFLUORO-PHENYL)-BUTYRIC ACID BOC-(R)-3-AMINO-4-(4-FLUORO-PHENYL)-BUTYRIC ACID 3-OXO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID METHYL ESTER Sitagliptin 243139-71-1 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione 762240-92-6 762240-99-3 Sitagliptin Defuoro IMpurity 3 2,3,5-TRIFLUOROPHENYLACETIC ACIDRelated product price
- ETHYLENE OXIDE
₹3644.2-160534.75 - Butyraldehyde
₹792-71450.01 - Sebacic acid
₹1080-97160