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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Bulk Drug Intermediates >Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate

Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate

Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate Structure
  • ₹0
  • Product name: Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate
  • CAS: 769195-26-8
  • MF: C11H9F3O3
  • MW: 246.19
  • EINECS:1308068-626-2
  • MDL Number:MFCD09833197
  • Synonyms:3-OXO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID METHYL ESTER;2,4,5-TRIFLUORO-BETA-OXO-BENZENEBUTANOIC ACID METHYL ESTER;Methyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate;4-(2,4,5 )triflorophenyl 3-oxobutanoic acid, Methy ester;3-oxo-4-(2,4,5-trifluorophenyl;Benzenebutanoicacid,2,4,5-trifluoro-b-oxo-,Methylester;Methyl 2,4,5-trifluoro-b-oxo-benzenebutanoate;Methyl 3-oxo-4-(2,4,5-trifluorophenyl)
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :40-41 °C
Boiling point :273.3±35.0 °C(Predicted)
Density :1.330±0.06 g/cm3(Predicted)
refractive index :1.469
Flash point :115.5±20.8 °C
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :9.95±0.46(Predicted)
color :Pale Yellow to Light Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate is a useful synthetic intermediate in the synthesis of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase (DPP) IV inhibitor for the treatment of type II diabetes.

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