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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Alkylating antineoplastic >Estramustine sodium phosphate

Estramustine sodium phosphate

Estramustine sodium phosphate Structure
  • ₹2619.65 - ₹10511.08
  • Product name: Estramustine sodium phosphate
  • CAS: 52205-73-9
  • MF: C23H33Cl2NNaO6P
  • MW: 544.38
  • EINECS:257-735-7
  • MDL Number:MFCD00866320
  • Synonyms:ESTRAMUSTINE PHOSPHATE SODIUM;-(dihydrogenphosphate),disodiumsalt ;iumphosphate ;Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt;Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt;Estracyt;Estramustine phosphate disodium salt;NSC 89199
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberE0407
  • Product descriptionEstramustine sodium phosphate
  • Packaging5MG
  • Price₹2619.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE0407
  • Product descriptionEstramustine sodium phosphate
  • Packaging25MG
  • Price₹10511.08
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) E0407 Estramustine sodium phosphate 5MG ₹2619.65 2022-06-14 Buy
Sigma-Aldrich(India) E0407 Estramustine sodium phosphate 25MG ₹10511.08 2022-06-14 Buy

Properties

storage temp. :Inert atmosphere,2-8°C
solubility :H2O: soluble50mg/mL
form :A crystalline solid
color :White to off-white
Stability :Hygroscopic, Unstable in Solution
CAS DataBase Reference :52205-73-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Estramustine phosphate is a derivative of estradiol (Item Nos. 20776 | 10006315) that contains a nor-nitrogen mustard group. Estramustine phosphate destabilizes microtubules by binding to microtubule-associated proteins (MAPs) with Kd values of 10 and 15 μM for MAP-1 and MAP-2, respectively. Estramustine induces cell cycle arrest in mitosis at the metaphase stage in DU145 and PC3 prostate cancer cells and induces apoptosis in U87MG human malignant glioma cells. The metabolites of estramustine phosphate have anti-androgenic effects. Formulations containing estramustine phosphate are used in the palliative treatment of prostate cancer.

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Estramustine Pentasodium triphosphate hexhydrate Sodium metaphosphate 2392-39-4 Digold trioxide 52205-73-9

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Suppliers and manufacturers

career henan chemical co
Estramustine sodium phosphate
₹3.00 /1KG
Estramustine sodium phosphate CAS:52205-73-9
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Xiamen AmoyChem Co., Ltd
CONIER CHEM AND PHARMA LIMITED
SIMAGCHEM CORP
Hefei TNJ Chemical Industry Co.,Ltd.