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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Alkylating antineoplastic >Estramustine

Estramustine

Estramustine Structure
  • ₹0
  • Product name: Estramustine
  • CAS: 2998-57-4
  • MF: C23H31Cl2NO3
  • MW: 440.4
  • EINECS:221-076-3
  • MDL Number:MFCD00866377
  • Synonyms:3,5(10)-triene-3,17-diol(17beta)-estra-3-(bis(2-chloroethyl)carbamate) ;LEO 275;1,3,5(10)-Estratriene-3,17β-diol 3-[bis(2-chloroethyl)carbamate];1,3,5(10)-Estratriene-3,17β-diol 3-[N,N-bis(2-chloroethyl)carbamate];Estamustine;estradiol,3-(bis(2-chloroethyl)carbamate) ;ESTRAMUSTINE;Estramustin
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :104-105°
alpha :D20 +50° (in dioxane)
Boiling point :565.8±50.0 °C(Predicted)
Density :1.253±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
form :Solid
pka :15.05±0.40(Predicted)
color :White to off-white
Water Solubility :1mg/L(30 ºC)
CAS DataBase Reference :2998-57-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Estradiol 3-[N,N-Bis(2-chloroethyl)carbamate] is used treatment of breast cancer. Also used in the treatment of prostate cancer.

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