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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Alkylating antineoplastic >Mechlorethamine hydrochloride

Mechlorethamine hydrochloride

Mechlorethamine hydrochloride Structure
  • ₹0
  • Product name: Mechlorethamine hydrochloride
  • CAS: 55-86-7
  • MF: C5H12Cl3N
  • MW: 192.51
  • EINECS:200-246-0
  • MDL Number:MFCD00012517
  • Synonyms:1,5-dichloro-3-methyl-3-azapentanehydrochloride ;2-chloro-n-(2-chloroethyl)-n-methylethanaminehydrochlroide ;2-chloro-n-(2-chloroethyl)-n-methyl-ethanaminhydrochloride ;antimit ;azotoyperite ;beta,beta’-dichlorodiethyl-n-methylaminehydrochloride ;c6866 ;caryolysine
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :108-111 °C(lit.)
Boiling point :315.95°C (rough estimate)
Density :1.4424 (rough estimate)
refractive index :1.6300 (estimate)
storage temp. :−20°C
solubility :H2O: very soluble
form :Solid
pka :pKa 6.43 (Uncertain)
color :Leaflets from Me2CO or CHCl3
Sensitive :Hygroscopic
Merck :13,5798
Stability :Stable. Hygroscopic.
CAS DataBase Reference :55-86-7(CAS DataBase Reference)
EPA Substance Registry System :Nitrogen mustard (HN-2), hydrochloride (55-86-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard.

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