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(3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one

(3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one Structure
  • ₹0
  • Product name: (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one
  • CAS: 63038-10-8
  • MF: C12H16O2
  • MW: 192.26
  • EINECS:
  • MDL Number:MFCD16660665
  • Synonyms:(3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one;(S)-3-Butyl-4,5-dihydroisobenzofuran-1(3H)-one;1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (S)-;(-)-Sedanenolide;(3S)-3-Butyl-4,5-dihydro-1(3H)-isobenzofuranone;(S)-Sedanenolide;3-Butyl-4,5-dihydrophthalide;1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (3S)-
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form :Liquid
color :Colorless to light yellow
LogP :1.775 (est)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Senkyunolide A is a phthalide originally isolated from celery seed essential oil that has cytoprotective and antiproliferative activities. It protects against cell injury induced by corticosterone in PC12 cells in a time-dependent manner when used at concentrations ranging from 0.125 to 0.5 mg/ml and reduces corticosterone-induced apoptosis at a concentration of 0.5 mg/ml. It also reverses increases in protein levels of phosphatase 2A (PP2A) and α-synuclein and reverses decreases in the phosphorylated forms of PP2A and α-synuclein. Senkyunolide A inhibits cell proliferation of HT-29 colon cancer (IC50 = 54.17 μM) but not non-cancerous human CCD-18Co colon cells (IC50 = 109.11 μM).

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Suppliers and manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Senkyunolide A
₹0.00 /25kg
Senkyunolide A CAS:63038-10-8
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
BOC Sciences
Hubei Ipure Biology Co., Ltd
Hefei TNJ Chemical Industry Co.,Ltd.
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd