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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >N-BUTYLIDENEPHTHALIDE

N-BUTYLIDENEPHTHALIDE

N-BUTYLIDENEPHTHALIDE Structure
  • ₹3095 - ₹43210
  • Product name: N-BUTYLIDENEPHTHALIDE
  • CAS: 551-08-6
  • MF: C12H12O2
  • MW: 188.22
  • EINECS:208-991-3
  • MDL Number:MFCD00047319
  • Synonyms:N-BUTYLIDENEPHTHALIDE;FEMA 3333;1(3H)-Isobenzofuranone,3-butylidene- ;3-butylidene-1(3h)-isobenzofuranon ;3-butylidene-1(3H)-Isobenzofuranone ;3-BUTYLIDENEPHTHALIDE 96+%;n-Butylidenephthalide,95%;3-Butylidene-1,3-dihydroisobenzofuran-1-one
3 prices
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Brand

  • ALFA India

Package

  • 10g
  • 50g
  • 250g
  • ManufacturerALFA India
  • Product numberALF-A10353-09
  • Product descriptionn-Butylidenephthalide, (E)+(Z), 95%
  • Packaging10g
  • Price₹3095
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A10353-18
  • Product descriptionn-Butylidenephthalide, (E)+(Z), 95%
  • Packaging50g
  • Price₹10294
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A10353-30
  • Product descriptionn-Butylidenephthalide, (E)+(Z), 95%
  • Packaging250g
  • Price₹43210
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-A10353-09 n-Butylidenephthalide, (E)+(Z), 95% 10g ₹3095 2022-05-26 Buy
ALFA India ALF-A10353-18 n-Butylidenephthalide, (E)+(Z), 95% 50g ₹10294 2022-05-26 Buy
ALFA India ALF-A10353-30 n-Butylidenephthalide, (E)+(Z), 95% 250g ₹43210 2022-05-26 Buy

Properties

Melting point :82.5°C
Boiling point :139-142 °C/5 mmHg (lit.)
Density :1.103 g/mL at 25 °C (lit.)
FEMA :3333 | 3-BUTYLIDENEPHTHALIDE
refractive index :n20/D 1.577(lit.)
Flash point :>230 °F
storage temp. :Refrigerator
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Oil
color :Colourless to Yellow
Odor :at 10.00 % in dipropylene glycol. herbal lovage celery
Odor Type :herbal
JECFA Number :1170
BRN :5145
InChIKey :WMBOCUXXNSOQHM-FLIBITNWSA-N
LogP :3.72
CAS DataBase Reference :551-08-6(CAS DataBase Reference)
EPA Substance Registry System :1(3H)-Isobenzofuranone, 3-butylidene- (551-08-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.

Description

N-Butylidenephthalide is a phthalide derivative useful for control of sensation disorder and olfaction disorder. It is a bioactive phthalide compound of Chuanxiong rhizoma, a Chinese herbal medicine used for treating headache obtained from the root of Ligusticum chuanxiong Hort. It has found that it can regulate tumor stem cell genes EZH2/AXL and reduced its migration and invasion in glioblastoma. Moreover, it can induce apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2a and telomerase activity. Therefore, it is a potential cancer chemotherapy drug. Moreover, It can also exhibit protection against neurotoxicity through regulation of tryptophan 2, 3 dioxygenase in spinocerebellar ataxia type 3. Finally, it has certain antiplatelet effect.

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