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ChemicalBook > Product Catalogue >API >Respiratory Drugs >Antitussives >Dextromethorphan hydrobromide monohydrate

Dextromethorphan hydrobromide monohydrate

Dextromethorphan hydrobromide monohydrate Structure
  • ₹7425.95 - ₹47186.18
  • Product name: Dextromethorphan hydrobromide monohydrate
  • CAS: 6700-34-1
  • MF: C18H28BrNO2
  • MW: 370.33
  • EINECS:629-741-3
  • MDL Number:MFCD02173901
  • Synonyms:DMHM ;(9α,13α,14α)-3-Methoxy-17-MethylMorphinan HydrobroMide Hydrate;3-Methoxy-17-Methyl-9α,13α,14α-Morphinan HydrobroMide Hydrate;d-3-Methoxy-N-MethylMorphinan HydrobroMide Monohydrate;DextroMethorphan hydrobroMide:Monohydrat;Morphinan,3-Methoxy-17-Methyl-, hydrobroMide, hydrate (1:1:1), (9a,13a,14a)-;D-3-METHOXY-N-METHYLMORPHINAN HYDROBROMIDE;DEXTROMETHORPHAN HYDROBROMIDE MONOHYDRATE
Price7 Properties Safety Information Description
7 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 500MG
  • 5G
  • 10G
  • 50G
  • ManufacturerSigma-Aldrich(India)
  • Product numberD2531
  • Product descriptionDextromethorphan hydrobromide monohydrate ≥99% (TLC)
  • Packaging50G
  • Price₹47186.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9684
  • Product descriptionDextromethorphan hydrobromide meets USP testing specifications
  • Packaging50G
  • Price₹33622.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD2531
  • Product descriptionDextromethorphan hydrobromide monohydrate ≥99% (TLC)
  • Packaging10G
  • Price₹13206.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9684
  • Product descriptionDextromethorphan hydrobromide meets USP testing specifications
  • Packaging5G
  • Price₹10370.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9684
  • Product descriptionDextromethorphan hydrobromide meets USP testing specifications
  • Packaging10G
  • Price₹10240.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1018
  • Product descriptionDextromethorphan HBr certified reference material, pharmaceutical secondary standard
  • Packaging500MG
  • Price₹9493.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD2531
  • Product descriptionDextromethorphan hydrobromide monohydrate ≥99% (TLC)
  • Packaging5G
  • Price₹7425.95
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D2531 Dextromethorphan hydrobromide monohydrate ≥99% (TLC) 50G ₹47186.18 2022-06-14 Buy
Sigma-Aldrich(India) D9684 Dextromethorphan hydrobromide meets USP testing specifications 50G ₹33622.45 2022-06-14 Buy
Sigma-Aldrich(India) D2531 Dextromethorphan hydrobromide monohydrate ≥99% (TLC) 10G ₹13206.5 2022-06-14 Buy
Sigma-Aldrich(India) D9684 Dextromethorphan hydrobromide meets USP testing specifications 5G ₹10370.35 2022-06-14 Buy
Sigma-Aldrich(India) D9684 Dextromethorphan hydrobromide meets USP testing specifications 10G ₹10240.45 2022-06-14 Buy
Sigma-Aldrich(India) PHR1018 Dextromethorphan HBr certified reference material, pharmaceutical secondary standard 500MG ₹9493.53 2022-06-14 Buy
Sigma-Aldrich(India) D2531 Dextromethorphan hydrobromide monohydrate ≥99% (TLC) 5G ₹7425.95 2022-06-14 Buy

Properties

Melting point :116-119°C
alpha :[α]D25 +26～+30° (c=1.85, H2O)
Flash point :11 °C
storage temp. :Store at RT
solubility :Sparingly soluble in water, freely soluble in ethanol (96 per cent).
form :solid
color :White to Off-White
PH :pH (10g/l, 25℃) : 5.2～6.5
BRN :6453793
InChIKey :QYPSYPPSHXDFLV-UHFFFAOYSA-N
LogP :1.351 (est)
CAS DataBase Reference :6700-34-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P391 Collect spillage. Hazardous to the aquatic environment
P405 Store locked up.

Description

Dextromethorphan (DXM) is a dextratrorotatory morphinan with structural similarity to levorphanol, codeine, and morphine. Because of its strong antitussive effects, dextromethorphan is widely used as a cough suppressant. However, it does not provoke opioid activity as is characteristic of several other morphine derivatives. DXM binds to and inhibits NMDA (IC50 = 0.55 μM) and nicotinic receptors (IC50s = 0.7-3.9 μM) and blocks receptor-gated and voltage-gated calcium channels (IC50 = 60 μM) and voltage-gated sodium channels (IC50 = 78 μM). DXM has been used in multimodal analgesic therapies for acute and neuropathic pain.

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