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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >7,8-Dihydroxyflavone

7,8-Dihydroxyflavone

7,8-Dihydroxyflavone Structure
  • ₹4800 - ₹34531.75
  • Product name: 7,8-Dihydroxyflavone
  • CAS: 38183-03-8
  • MF: C15H10O4
  • MW: 254.24
  • EINECS:253-812-4
  • MDL Number:MFCD00006836
  • Synonyms:7,8-DIHYDROXYFLAVONE;DIHYDROXYFLAVONE, 7,8-(RG);7,8-dihydroxy-2-phenyl-4h-1-benzopyran-4-on ;TIMTEC-BB SBB000930;DIHYDROXYFLAVONE, 7,8-;7,8-Dihydroxy-2-phenyl-4H-chroMen-4-one;4H-1-Benzopyran-4-one,7,8-dihydroxy-2-phenyl-;2-Phenyl-7,8-dihydroxy-4H-1-benzopyran-4-one
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 100MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberD1916
  • Product description7,8-Dihydroxyflavone
  • Packaging1G
  • Price₹4800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD5446
  • Product description7,8-Dihydroxyflavone hydrate ≥98% (HPLC)
  • Packaging10MG
  • Price₹8746.6
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD1916
  • Product description7,8-Dihydroxyflavone
  • Packaging5G
  • Price₹15000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.06300
  • Product descriptionTrkB Agonist, 7,8-Dihydroxyflavone - CAS 38183-03-8 - Calbiochem
  • Packaging100MG
  • Price₹24770.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD5446
  • Product description7,8-Dihydroxyflavone hydrate ≥98% (HPLC)
  • Packaging50MG
  • Price₹34531.75
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D1916 7,8-Dihydroxyflavone 1G ₹4800 2022-05-26 Buy
Sigma-Aldrich(India) D5446 7,8-Dihydroxyflavone hydrate ≥98% (HPLC) 10MG ₹8746.6 2022-06-14 Buy
TCI Chemicals (India) D1916 7,8-Dihydroxyflavone 5G ₹15000 2022-05-26 Buy
Sigma-Aldrich(India) 5.06300 TrkB Agonist, 7,8-Dihydroxyflavone - CAS 38183-03-8 - Calbiochem 100MG ₹24770.01 2022-06-14 Buy
Sigma-Aldrich(India) D5446 7,8-Dihydroxyflavone hydrate ≥98% (HPLC) 50MG ₹34531.75 2022-06-14 Buy

Properties

Melting point :243-246°C
Boiling point :494.4±45.0 °C(Predicted)
Density :1.443±0.06 g/cm3(Predicted)
FEMA :4830 | 7,8-DIHYDROXYFLAVONE
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: soluble24mg/mL
form :solid
pka :6.86±0.40(Predicted)
color :Yellow or tan
Stability :Stable for 1 year from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 week.
InChI :InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H
InChIKey :COCYGNDCWFKTMF-UHFFFAOYSA-N
SMILES :C1(C2=CC=CC=C2)OC2=C(O)C(O)=CC=C2C(=O)C=1
LogP :2.760 (est)
CAS DataBase Reference :38183-03-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

7,8-Dihydroxyflavone (7,8-DHF) is a monophenolic flavone with diverse effects. It acts as an agonist of the neurotrophic tyrosine kinase receptor TrkB (Kd = 320 nM), protecting neurons that express TrkB from apoptosis. 7,8-DHF is neuroprotective in an animal model of Parkinson’s disease. It supports emotional learning in mice and reverses memory deficits in a mouse model of Alzheimer’s disease. It also improves motor function and extends survival in an animal model of Huntington’s disease. 7,8-DHF inhibits the cytochrome P450 aromatase (IC50 = 10 μM) and, in this way, alters estrogen metabolism. It also has antioxidant action that increases intracellular glutathione synthesis and scavenges reactive oxygen species.

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Suppliers and manufacturers

Wuhan Nutra Biotechnology Co.,Ltd
7,8-Dihydroxyflavone hydrate;7,8-DHF
₹0.00 /100g
7,8-Dihydroxyflavone hydrate;7,8-DHF CAS:38183-03-8
Wuhan senwayer century chemical Co.,Ltd
7,8-DIHYDROXYFLAVONE
₹3300.00 /1kg
7,8-DIHYDROXYFLAVONE CAS:38183-03-8
GLR Innovations OCIMUM LIFESCIENCES PVT LTD CLEARSYNTH LABS LTD. A.J Chemicals Biosyn Research Chemicals Evans Fine Chem TCI Chemicals (India) Pvt. Ltd.
Tianjin Kilo Pharmaceutical Sci-Tech Co., Ltd