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7-KETOCHOLESTEROL

7-KETOCHOLESTEROL Structure
  • ₹5856.33 - ₹25373.8
  • Product name: 7-KETOCHOLESTEROL
  • CAS: 566-28-9
  • MF: C27H44O2
  • MW: 400.65
  • EINECS:
  • MDL Number:MFCD00010474
  • Synonyms:7-KETOCHOLESTEROL;5-CHOLESTEN-3BETA-OL-7-ONE;3BETA-HYDROXY-5-CHOLESTEN-7-ONE;Cholest-5-en-3beta-ol-7-one;3-hydroxy-5-cholestene-7-one;(3-beta)-cholest-5-en-7-on ;3-beta-hydroxy-cholest-5-en-7-on ;3-HYDROXY-5-CHOLESTENE-7-ONE;7-KETOCHOLESTEROL
Price3 Properties Safety Information Description
3 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 250MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberC2394
  • Product description5-Cholesten-3β-ol-7-one ≥90%
  • Packaging100MG
  • Price₹5856.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC2394
  • Product description5-Cholesten-3β-ol-7-one ≥90%
  • Packaging250MG
  • Price₹11734.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC2394
  • Product description5-Cholesten-3β-ol-7-one ≥90%
  • Packaging1G
  • Price₹25373.8
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C2394 5-Cholesten-3β-ol-7-one ≥90% 100MG ₹5856.33 2022-06-14 Buy
Sigma-Aldrich(India) C2394 5-Cholesten-3β-ol-7-one ≥90% 250MG ₹11734.3 2022-06-14 Buy
Sigma-Aldrich(India) C2394 5-Cholesten-3β-ol-7-one ≥90% 1G ₹25373.8 2022-06-14 Buy

Properties

Melting point :158-160°C
Boiling point :463.26°C (rough estimate)
Density :1.0044 (rough estimate)
refractive index :1.4480 (estimate)
storage temp. :room temp
solubility :Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :14.68±0.70(Predicted)
color :Crystals from CHCl3/Et2O

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

7-keto Cholesterol is a bioactive sterol that can affect cholesterol homeostasis, membrane properties and cell survival. It strongly inhibits cytochrome P450 7A1 (CYP7A1), the cholesterol 7α-hydroxylase, with an IC50 = ~ 1 μM. 7-keto Cholesterol can be produced by oxidation of cholesterol associated with ethanol-mediated lipid peroxidation or photodamage. It can also be derived enzymatically by oxidation of 7-dehydrocholesterol, the immediate precursor of cholesterol, by CYP7A1, while 11β-hydroxysteroid dehydrogenase type 1 stimulates its reduction. 7-keto Cholesterol is a major oxysterol component of oxidized LDL. This compound can be used as a standard in the determination of cholesterol derivatives by GC-MS or HPLC.

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7BETA-HYDROXYCHOLESTEROL 25-HYDROXYCHOLESTEROL 5-CHOLESTEN-3-BETA, 7-ALPHA-DIOL Cholesterol

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