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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Serine derivatives >FMOC-O-tert-Butyl-L-serine

FMOC-O-tert-Butyl-L-serine

FMOC-O-tert-Butyl-L-serine Structure
  • ₹1800 - ₹102720
  • Product name: FMOC-O-tert-Butyl-L-serine
  • CAS: 71989-33-8
  • MF: C22H25NO5
  • MW: 383.44
  • EINECS:276-260-6
  • MDL Number:MFCD00037127
  • Synonyms:O-tert-Butyl-N-Fmoc-L-serine;9-fluorenylmethoxycarbonyl-O-tert-butyl-L-serine;N-Fmoc-O-tert-Butyl-L-serine, Fmoc-O-tert-butyl-L-serine;N-FMOC-L-Ser (O-tert-Bu) OH;2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]propanoic acid;N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butyl-L-serine;N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butylserine;N-Fmoc-O-tert-Butylserine
14 prices
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Brand

  • Sigma-Aldrich(India)
  • ALFA India
  • TCI Chemicals (India)
  • SRL

Package

  • 5g
  • 10G
  • 25G
  • 100G
  • 250G
  • 1KG
  • 10Gms
  • 100Gms
  • ManufacturerSigma-Aldrich(India)
  • Product number8.52019
  • Product descriptionFmoc-Ser(tBu)-OH Novabiochem?
  • Packaging1KG
  • Price₹102720
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number47619
  • Product descriptionFmoc-Ser(tBu)-OH ≥98.0% (HPLC)
  • Packaging1KG
  • Price₹77442.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.52019
  • Product descriptionFmoc-Ser(tBu)-OH Novabiochem?
  • Packaging250G
  • Price₹29660.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number47619
  • Product descriptionFmoc-Ser(tBu)-OH ≥98.0% (HPLC)
  • Packaging100G
  • Price₹26683.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.52019
  • Product descriptionFmoc-Ser(tBu)-OH Novabiochem?
  • Packaging100G
  • Price₹13880
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number47619
  • Product descriptionFmoc-Ser(tBu)-OH ≥98.0% (HPLC)
  • Packaging25G
  • Price₹12708.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number47619
  • Product descriptionFmoc-Ser(tBu)-OH ≥98.0% (HPLC)
  • Packaging10G
  • Price₹6776.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.52019
  • Product descriptionFmoc-Ser(tBu)-OH Novabiochem?
  • Packaging25G
  • Price₹5800.01
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-H59422-14
  • Product descriptionN-Fmoc-O-tert-butyl-L-serine, 97%
  • Packaging25g
  • Price₹8096
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-H59422-06
  • Product descriptionN-Fmoc-O-tert-butyl-L-serine, 97%
  • Packaging5g
  • Price₹3033
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3168
  • Product descriptionO-tert-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine
  • Packaging5G
  • Price₹1800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3168
  • Product descriptionO-tert-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine
  • Packaging25G
  • Price₹6500
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number13334
  • Product descriptionFMOC-O-Tert-Butyl-L-Serine (FMOC-Ser(tBu)-OH) extrapure, 99%
  • Packaging10Gms
  • Price₹3510
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number13334
  • Product descriptionFMOC-O-Tert-Butyl-L-Serine (FMOC-Ser(tBu)-OH) extrapure, 99%
  • Packaging100Gms
  • Price₹22200
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 8.52019 Fmoc-Ser(tBu)-OH Novabiochem? 1KG ₹102720 2022-06-14 Buy
Sigma-Aldrich(India) 47619 Fmoc-Ser(tBu)-OH ≥98.0% (HPLC) 1KG ₹77442.05 2022-06-14 Buy
Sigma-Aldrich(India) 8.52019 Fmoc-Ser(tBu)-OH Novabiochem? 250G ₹29660.01 2022-06-14 Buy
Sigma-Aldrich(India) 47619 Fmoc-Ser(tBu)-OH ≥98.0% (HPLC) 100G ₹26683.63 2022-06-14 Buy
Sigma-Aldrich(India) 8.52019 Fmoc-Ser(tBu)-OH Novabiochem? 100G ₹13880 2022-06-14 Buy
Sigma-Aldrich(India) 47619 Fmoc-Ser(tBu)-OH ≥98.0% (HPLC) 25G ₹12708.55 2022-06-14 Buy
Sigma-Aldrich(India) 47619 Fmoc-Ser(tBu)-OH ≥98.0% (HPLC) 10G ₹6776.45 2022-06-14 Buy
Sigma-Aldrich(India) 8.52019 Fmoc-Ser(tBu)-OH Novabiochem? 25G ₹5800.01 2022-06-14 Buy
ALFA India ALF-H59422-14 N-Fmoc-O-tert-butyl-L-serine, 97% 25g ₹8096 2022-05-26 Buy
ALFA India ALF-H59422-06 N-Fmoc-O-tert-butyl-L-serine, 97% 5g ₹3033 2022-05-26 Buy
TCI Chemicals (India) B3168 O-tert-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine 5G ₹1800 2022-05-26 Buy
TCI Chemicals (India) B3168 O-tert-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine 25G ₹6500 2022-05-26 Buy
SRL 13334 FMOC-O-Tert-Butyl-L-Serine (FMOC-Ser(tBu)-OH) extrapure, 99% 10Gms ₹3510 2022-05-26 Buy
SRL 13334 FMOC-O-Tert-Butyl-L-Serine (FMOC-Ser(tBu)-OH) extrapure, 99% 100Gms ₹22200 2022-05-26 Buy

Properties

Melting point :130.5-135.5 °C(lit.)
alpha :25 º (c=1,EtOAc 24 ºC)
Boiling point :510.36°C (rough estimate)
Density :1.2369 (rough estimate)
refractive index :24 ° (C=1, AcOEt)
storage temp. :2-8°C
solubility :Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form :powder to crystal
pka :3.44±0.10(Predicted)
color :White to Almost white
optical activity :[α]20/D +25.5±1°, c = 1% in ethyl acetate
BRN :3632013
InChI :InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChIKey :REITVGIIZHFVGU-IBGZPJMESA-N
SMILES :C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference :71989-33-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:
  • Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
  • Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
  • Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.


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