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FMOC-O-tert-Butyl-L-serine

FMOC-O-tert-Butyl-L-serine Structure
CAS No.
71989-33-8
Chemical Name:
FMOC-O-tert-Butyl-L-serine
Synonyms
FMOC-SER(TBU)-OH;FMOC-SER(TBU);FMOC-L-SER(TBU)-OH;FMOC-SER(BUT);Fomc-Ser(tBu)-OH;FMOC-L-Ser(tBu)-OH 98%;Fomc-Ser(t;Fmoc-Ser(OBut);FMOC-L-SER(T-BU);FMOC-SER(BUT)-OH
CBNumber:
CB4315210
Molecular Formula:
C22H25NO5
Molecular Weight:
383.44
MOL File:
71989-33-8.mol
MSDS File:
SDS
Modify Date:
2023/12/7 16:07:34

FMOC-O-tert-Butyl-L-serine Properties

Melting point 130.5-135.5 °C(lit.)
alpha 25 º (c=1,EtOAc 24 ºC)
Boiling point 510.36°C (rough estimate)
Density 1.2369 (rough estimate)
refractive index 24 ° (C=1, AcOEt)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder to crystal
pka 3.44±0.10(Predicted)
color White to Almost white
optical activity [α]20/D +25.5±1°, c = 1% in ethyl acetate
BRN 3632013
InChI InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChIKey REITVGIIZHFVGU-IBGZPJMESA-N
SMILES C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference 71989-33-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36/37/39-27-26
WGK Germany  3
HS Code  29242990
NFPA 704
0
0 0

FMOC-O-tert-Butyl-L-serine price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 8.52019 Fmoc-Ser(tBu)-OH Novabiochem? 71989-33-8 25G ₹5800.01 2022-06-14 Buy
Sigma-Aldrich(India) 8.52019 Fmoc-Ser(tBu)-OH Novabiochem? 71989-33-8 100G ₹13880 2022-06-14 Buy
Sigma-Aldrich(India) 8.52019 Fmoc-Ser(tBu)-OH Novabiochem? 71989-33-8 250G ₹29660.01 2022-06-14 Buy
Sigma-Aldrich(India) 8.52019 Fmoc-Ser(tBu)-OH Novabiochem? 71989-33-8 1KG ₹102720 2022-06-14 Buy
Sigma-Aldrich(India) 47619 Fmoc-Ser(tBu)-OH ≥98.0% (HPLC) 71989-33-8 10G ₹6776.45 2022-06-14 Buy
Product number Packaging Price Buy
8.52019 25G ₹5800.01 Buy
8.52019 100G ₹13880 Buy
8.52019 250G ₹29660.01 Buy
8.52019 1KG ₹102720 Buy
47619 10G ₹6776.45 Buy

FMOC-O-tert-Butyl-L-serine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:

  • Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
  • Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
  • Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.

General Description

The product number for this product was previously 04-12-1033.

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FMOC-O-tert-Butyl-L-serine Spectrum

O-tert-Butyl-N-Fmoc-L-serine 9-fluorenylmethoxycarbonyl-O-tert-butyl-L-serine N-Fmoc-O-tert-Butyl-L-serine, Fmoc-O-tert-butyl-L-serine N-FMOC-L-Ser (O-tert-Bu) OH 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]propanoic acid N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butyl-L-serine N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butylserine N-Fmoc-O-tert-Butylserine O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine O-tert-Butyl-N-(9H-fluorene-9-ylmethoxycarbonyl)-L-serine O-tert-Butyl-N-Fmoc-Ser-OH FMOC-O-tert-Butyl-L-serine,98% Fmoc-Ser(tBu)-OH ,99% (S)-tert-butyl 2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)-3-hydroxypropanoate FMoc-Ser(tBu)-OH FMoc-O-tert·butyl-L-serine O-tert-Butyl-N-Fmoc-L-serine Fmoc-Ser(tBu)-OH N-FMOC-O-TERT-BUTYL-L-SERINE 97% N-FMOC-O-TERT-BUTYL-L-SERINE 98+% Fmoc-Ser(tBu)-OH >=98.0% (HPLC) O-(tert-butyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine N-9-FLUORENYLMETHYLOXYCARBONYL-O-TERT-BUTYL-L-SERINE N-9-FLUORENYLMETHYLOXYCARBONYL-O-T-BUTYL-L-SERINE N-(9-FLUORENYL METHOXY CARBONYL)-O-TERT-BUTYL-L-SERINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TERT-BUTYL-L-SERINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-T-BUTYL-L-SERINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-T-BUTYL-L-SERINE FMOC-L-SERINE(O-T-BUTYL) FMOC-L-SERINE (TBU) FMOC-L-SER(O-T-BUTYL) FMOC-L-SER(T-BU) FMOC-O-T-BUTYL-L-SERINE FMOC-O-TERT-BUTYL-L-SERINE FMOC-SERINE(TBU)-OH FMOC-SER(BUT)-OH 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-SERINE Fmoc-Ser(tBu)-OH(CAS:71989-33-8) (S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(tert-butoxy)propanoic acid L-Serine-UL-13C3, 15N-N-FMOC L-Serine, O-(1,1-dimethylethyl)-N-(9H-fluoren-9-ylmethoxy)carbonyl- N-FMOC-O-TERT-BUTYL-L-SERINE N-FMOC-SER(T-BU)-OH NALPHA-9-Fluorenylmethoxycarbonyl-O-tert-butyl-L-serine FMOC-O-TERT-BUTYL-L-SERINE (FMOC-L-SER(TBU)-OH) N-(9-FLUORENYLMETHOXYCARBONYL)-2-TERT-BUTYL-L-SERINE L-SERINE-N-FMOC, O-TERT-BUTYL ETHER (1-13C) L-SERINE-N-FMOC, O-TERT-BUTYL ETHER (13C3,15N) Fmoc-O-tert-butyl-L-serine≥ 99.7% (HPLC, Chiral purity) N-FMOC-O-T-BUTYL-L-SERINE N-FMOC-T-BUTYL-L-SER N-ALPHA-FMOC-O-TERT-BUTYL-L-SERINE N-ALPHA-FMOC-O-T-BUTYL-L-SERINE O-tert-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine > FMOC-SER(TBU)-OH 250 G FMOC-SER(TBU)-OH 100 G FMOC-SER(TBU)-OH 25 G CAS71989-33-8 FMOC-O-tert-Butyl-L-serine FMOC-O-Tert-Butyl-L-Serine (FMOC-Ser(tBu)-OH) extrapure, 99% (9H-Fluoren-9-yl)MethOxy]Carbonyl Ser(tBu)-OH