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ChemicalBook > Product Catalogue >Organic Chemistry >Amides >N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Structure
  • ₹0
  • Product name: N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide
  • CAS: 76820-34-3
  • MF: C14H19N3O8
  • MW: 357.32
  • EINECS:616-392-7
  • MDL Number:MFCD06657564
  • Synonyms:N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-5-NITRO-1,3-BENZENEDICARBOXAMIDE;N,N`-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenediformamide;N,N-Bis-(2,3-dihydroxypropyl)-5-nitroisophthalamide;5-AMINO C N,N'' C BIS (2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-1,3-BENZENEDICARBOXAMIDE;N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide;5-Nitro-N,NBis(2,3-Dihydroxypropyl)-1,3-Benzenedicarbolamide;Iohexol Related Compound C (50 mg) (N,N'-bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide);5-Nitro-N,N'-bis(2,3-dihydroxypropyl)isophthalamide
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>140°C (dec.)
Density :1.347 at 20℃
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form :Solid
color :White to Off-White
Stability :Hygroscopic
LogP :-1.36 at 23℃ and pH6
CAS DataBase Reference :76820-34-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is a non-ionic organic compound that can be used as a reaction intermediate for the preparation of amidated iodinated x-ray contrast media. The amidation reaction is typically carried out in aqueous solution with an acid catalyst at room temperature for up to 24 hours. The amidation reaction condition and time can be optimized depending on the desired end product. Industrial preparation of iohexol typically involves the use of an x-ray generator and iopamidol, which is synthesized from diethylene triamine and ethylenediamine.

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