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ChemicalBook > Product Catalogue >Biochemical Engineering >Nucleoside drugs >Nucleotides and their analogs >8-Bromoguanosine

8-Bromoguanosine

8-Bromoguanosine Structure
  • ₹0
  • Product name: 8-Bromoguanosine
  • CAS: 4016-63-1
  • MF: C10H12BrN5O5
  • MW: 362.14
  • EINECS:223-677-6
  • MDL Number:MFCD00037985
  • Synonyms:8-Bromo-D-guanosine;8-BROMOGUANOSINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM;2-AMINO-8-BROMO-6-HYDROXYPURINE RIBOSIDE;8-BROMOGUANOSINE;8-Bromoguanosine ,98%;8-Br-G;2-aMino-8-broMo-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one;NSC 174257
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :222°C
Boiling point :774.0±70.0 °C(Predicted)
Density :2.62±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO, Methanol (Sparingly), Hot Water
pka :13.00±0.70(Predicted)
form :Powder
color :Off-white
BRN :578725
CAS DataBase Reference :4016-63-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning GHS hazard pictograms P234, P390, P404
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P234 Keep only in original container.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363 Wash contaminated clothing before reuse.
P370+P378 In case of fire: Use … for extinction.
P390 Absorb spillage to prevent material damage.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P406 Store in corrosive resistant/… container with a resistant inner liner.

Description

8-Bromoguanosine is a brominated derivative of guanosine. Purine nucleobases with bromine at position eight are known to preferentially adopt the syn conformation as nucleosides and, thus, can be used to reduce the conformational heterogeneity of RNA to potentially enhance its function. It is reported to activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects.

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