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ChemicalBook > Product Catalogue >API >Specialty drugs >Dermatology drugs >8-Methoxypsoralen

8-Methoxypsoralen

8-Methoxypsoralen Structure
  • ₹1800 - ₹14094.15
  • Product name: 8-Methoxypsoralen
  • CAS: 298-81-7
  • MF: C12H8O4
  • MW: 216.19
  • EINECS:206-066-9
  • MDL Number:MFCD00005009
  • Synonyms:8-Methoxy-2',3',6,7-furocoumarin;8-methoxy-2’,3’,6,7-furocoumarin ;8-Methoxy-4',5',6,7-furocoumarin;8-Methoxy-4',5':6,7-furocoumarin;8-methoxy-4’,5’,6,7-furocoumarin ;8-methoxy-4’,5’:6,7-furocoumarin ;8-Methoxy-6,7-furanocoumarin;8-Methoxyfuranocoumarin
Price6 Properties Safety Information Description
6 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 100MG
  • 500MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberX0009
  • Product descriptionXanthotoxin min. 98.0 %
  • Packaging100MG
  • Price₹1800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberX0009
  • Product descriptionXanthotoxin min. 98.0 %
  • Packaging1G
  • Price₹3600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM3501
  • Product description8-Methoxypsoralen analytical standard
  • Packaging1G
  • Price₹3539.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number56448
  • Product descriptionXanthotoxin analytical standard
  • Packaging50MG
  • Price₹9601.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR3040
  • Product descriptionMethoxsalen pharmaceutical secondary standard, certified reference material
  • Packaging500MG
  • Price₹12394.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM3501
  • Product description8-Methoxypsoralen analytical standard
  • Packaging5G
  • Price₹14094.15
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) X0009 Xanthotoxin min. 98.0 % 100MG ₹1800 2022-05-26 Buy
TCI Chemicals (India) X0009 Xanthotoxin min. 98.0 % 1G ₹3600 2022-05-26 Buy
Sigma-Aldrich(India) M3501 8-Methoxypsoralen analytical standard 1G ₹3539.78 2022-06-14 Buy
Sigma-Aldrich(India) 56448 Xanthotoxin analytical standard 50MG ₹9601.78 2022-06-14 Buy
Sigma-Aldrich(India) PHR3040 Methoxsalen pharmaceutical secondary standard, certified reference material 500MG ₹12394.63 2022-06-14 Buy
Sigma-Aldrich(India) M3501 8-Methoxypsoralen analytical standard 5G ₹14094.15 2022-06-14 Buy

Properties

Melting point :148-150 °C(lit.)
Boiling point :276.6°C (rough estimate)
Density :1.1344 (rough estimate)
refractive index :1.4270 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :H2O: slightly soluble
form :Needle-Like Crystals or Powder
color :white to yellow
Water Solubility :PRACTICALLY INSOLUBLE
Merck :14,5988
BRN :196453
LogP :1.523 (est)
CAS DataBase Reference :298-81-7(CAS DataBase Reference)
NIST Chemistry Reference :Methoxsalen(298-81-7)
IARC :1 (Vol. 24, Sup 7, 100A) 2012
EPA Substance Registry System :Methoxsalen (298-81-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

8-methoxypsoralen (also known as methoxsalen) is a naturally occurring furocoumarin compound existing in several species of plants such as Psoralea corylifolia. It is a photoactive substance that can form DNA adducts upon UVA irradiation. It is a drug used for the treatment of psoriasis, eczema, vitiligo, and some kinds of cutaneous lymphomas associated with the exposure of skin to the UVA or light from lamps or sunlight. Its mechanism of action is through inhibiting the synthesis of the deoxyribonucleic acid (DNA). After the activation, it can preferentially bind to the guanine and cytosine molecules of DNA, further leading to the cross-linking of DNA, thus inhibiting the DNA synthesis. It can further inhibit the RNA and protein synthesis at high concentration. It is extracted from Ammi majus.

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