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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Anti-tuberculous mycobacterium leprae drugs >4,4'-Diaminodiphenylsulfone

4,4'-Diaminodiphenylsulfone

4,4'-Diaminodiphenylsulfone Structure
  • ₹1980 - ₹12535.35
  • Product name: 4,4'-Diaminodiphenylsulfone
  • CAS: 80-08-0
  • MF: C12H12N2O2S
  • MW: 248.3
  • EINECS:201-248-4
  • MDL Number:MFCD00007887
  • Synonyms:FREE SAMPLE NCV 4,4-DIAMINO DIPHENYL SULPHONE STD;4,4′-Diaminodiphenyl sulfone 4,4′-Sulfonyldianiline 4-Aminophenyl sulfone DDS Bis(4-aminophenyl) sulfone DDS;4,4'-Diaminodiphenyl sulfone for synthesis;BIS(P-AMINOPHENYL)SULFONE;EPORAL;DISULONE;DUMITONE;DIPHENASONE
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 250MG
  • 1G
  • 5G
  • 25G
  • 100G
  • 100gm
  • 250G
  • 500G
  • ManufacturerTCI Chemicals (India)
  • Product numberD0089
  • Product descriptionBis(4-aminophenyl) Sulfone
  • Packaging25G
  • Price₹2100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD0089
  • Product descriptionBis(4-aminophenyl) Sulfone
  • Packaging100G
  • Price₹2900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD0089
  • Product descriptionBis(4-aminophenyl) Sulfone
  • Packaging500G
  • Price₹5600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.21073
  • Product description4,4′-Diaminodiphenyl sulfone for synthesis
  • Packaging5G
  • Price₹1980
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number46158
  • Product descriptionDapsone VETRANAL?, analytical standard
  • Packaging250MG
  • Price₹4665.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA74807
  • Product description4-Aminophenyl sulfone 97%
  • Packaging100G
  • Price₹5390.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.21073
  • Product description4,4′-Diaminodiphenyl sulfone for synthesis
  • Packaging250G
  • Price₹6710
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1464
  • Product descriptionDapsone Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9103.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA74807
  • Product description4-Aminophenyl sulfone 97%
  • Packaging500G
  • Price₹12535.35
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number D 1385
  • Product description4,4'-Diaminodiphenylsulphone 98%
  • Packaging100gm
  • Price₹3204
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D0089 Bis(4-aminophenyl) Sulfone 25G ₹2100 2022-05-26 Buy
TCI Chemicals (India) D0089 Bis(4-aminophenyl) Sulfone 100G ₹2900 2022-05-26 Buy
TCI Chemicals (India) D0089 Bis(4-aminophenyl) Sulfone 500G ₹5600 2022-05-26 Buy
Sigma-Aldrich(India) 8.21073 4,4′-Diaminodiphenyl sulfone for synthesis 5G ₹1980 2022-06-14 Buy
Sigma-Aldrich(India) 46158 Dapsone VETRANAL?, analytical standard 250MG ₹4665.58 2022-06-14 Buy
Sigma-Aldrich(India) A74807 4-Aminophenyl sulfone 97% 100G ₹5390.85 2022-06-14 Buy
Sigma-Aldrich(India) 8.21073 4,4′-Diaminodiphenyl sulfone for synthesis 250G ₹6710 2022-06-14 Buy
Sigma-Aldrich(India) PHR1464 Dapsone Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9103.83 2022-06-14 Buy
Sigma-Aldrich(India) A74807 4-Aminophenyl sulfone 97% 500G ₹12535.35 2022-06-14 Buy
ottokemi D 1385 4,4'-Diaminodiphenylsulphone 98% 100gm ₹3204 2022-05-26 Buy

Properties

Melting point :175-177 °C(lit.)
Boiling point :511.7±35.0 °C(Predicted)
Density :1.2701 (rough estimate)
vapor pressure :0.004Pa at 25℃
refractive index :1.5950 (estimate)
storage temp. :2-8°C
solubility :0.38g/l
form :Crystalline Powder
pka :pKb 13.0(at 25℃)
color :White to beige
PH :5.5-7.5 (H2O, 20℃)(saturated aqueous solution)
Water Solubility :<0.1 g/100 mL at 20 ºC
Merck :14,2822
BRN :788055
BCS Class :4,2
Stability :Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey :MQJKPEGWNLWLTK-UHFFFAOYSA-N
LogP :0.97 at 25℃
CAS DataBase Reference :80-08-0(CAS DataBase Reference)
NIST Chemistry Reference :Dapsone(80-08-0)
IARC :3 (Vol. 24, Sup 7) 1987
EPA Substance Registry System :Dapsone (80-08-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. It is a second-line medication for the treatment and prevention of Pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne as well as other skin conditions. Moreover it is employed as an anti-inflammatory drug, anti-infective drug, a leprostatic drug and an antimalarial drug.

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