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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one

3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one

3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one Structure
  • ₹0
  • Product name: 3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one
  • CAS: 86499-96-9
  • MF: C10H10BrNO
  • MW: 240.1
  • EINECS:
  • MDL Number:MFCD03085918
  • Synonyms:A-BROMOBENZOCAPROLACTAM;ALPHA-BROMOBENZO-CAPROLACTAM;3-Bromobenzocaprolactam 3-Bromo-2,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one;3-Bromo-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one;3-bromobenzocaprolactam;3-bromo-1,3,4,5-tetrahdro-2h-benzazepin-2-one;3-BROMO-1,3,4,5-TETRAHYDRO-2H-1-BENZAZEPIN-2-ONE;3-BROMO-1,3,4,5-TETRAHYDRO-2H-1-BENZAZEPINE-2-ONE
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :164 °C
Boiling point :383.2±42.0 °C(Predicted)
Density :1.492±0.06 g/cm3(Predicted)
Flash point :185.542℃
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :slightly soluble in ethanol, benzene, acetone, insoluble in water
pka :13.59±0.40(Predicted)
CAS DataBase Reference :86499-96-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one is an intermediate in the synthesis of Benazepril Hydrochloride. Benazepril Hydrochloride is a first-line antihypertensive drug recommended by the WHO. It is a chiral drug with excellent clinical efficacy, strong safety and tiny side effects in the international antihypertensive drugs of angiotensin converting enzyme inhibitors.

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