5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine
![5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine Structure](/CAS/GIF/865362-74-9.gif)
|
- ₹7300 - ₹63964.93
- Product name: 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine
- CAS: 865362-74-9
- MF: C18H13N7
- MW: 327.34
- EINECS:
- MDL Number:MFCD14585805
- Synonyms:5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine;LM-3319 FR 180204;FR 180204;1H-Pyrazolo[3,4-c]pyridazin-3-amine, 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-;5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine FR 180204;5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine;ERK Inhibitor II, FR180204;FR 180204, 98%, a potent and selective ATP-competitive inhibitor of ERK
4 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0320
- Product descriptionFR180204 ≥98% (HPLC)
- Packaging5MG
- Price₹16161.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0320
- Product descriptionFR180204 ≥98% (HPLC)
- Packaging25MG
- Price₹63964.93
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberF1214
- Product descriptionFR 180204
- Packaging25MG
- Price₹19800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberF1214
- Product descriptionFR 180204
- Packaging5MG
- Price₹7300
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0320 | FR180204 ≥98% (HPLC) | 5MG | ₹16161.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0320 | FR180204 ≥98% (HPLC) | 25MG | ₹63964.93 | 2022-06-14 | Buy |
| TCI Chemicals (India) | F1214 | FR 180204 | 25MG | ₹19800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | F1214 | FR 180204 | 5MG | ₹7300 | 2022-05-26 | Buy |
Properties
Melting point :267 °C
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :7.19±0.50(Predicted)
form :Yellow solid
color :faint yellow to dark yellow
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :7.19±0.50(Predicted)
form :Yellow solid
color :faint yellow to dark yellow
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
The extracellular regulated kinases 1 and 2 (ERK1/2) are functionally redundant kinases activated by a variety of growth factors and mitogens. FR180204 is a potent cell-permeable inhibitor of ERK1 and ERK2 (Ki = 310 and 140 nM, respectively). It is much less effective against p38α (IC50 = 10 μM) and does not inhibit a range of other serine/threonine or tyrosine kinases. FR180204 blocks ERK-mediated signaling from TGF-β to AP-1 (IC50 = 3.1 μM). It attenuates delayed-type hypersensitivity in collagen-immunized mice and ameliorates collagen-induced arthritis in mice.More related product prices
LY 294002 HYDROCHLORIDE SCH772984 SB 203580 1,9-Pyrazoloanthrone MK-2206 2HClRelated product price
- LY 294002 HYDROCHLORIDE
₹10660-37350 - SB 203580
₹6500-37350 - 1,9-Pyrazoloanthrone
₹6100-60295.25
Suppliers and manufacturers
career henan chemical co
![5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine](https://img.chemicalbook.com/ProductImageEN/2019-12/small/ba6366e3-3f8d-40fa-ba09-4aeee2cfb7bd.png)
TCI Chemicals (India) Pvt. Ltd.
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
LEAPCHEM CO., LTD.
₹1.00 /1KG
5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine CAS:865362-74-9
5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine CAS:865362-74-9