5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine
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- ₹7300 - ₹63964.93
- Product name: 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine
- CAS: 865362-74-9
- MF: C18H13N7
- MW: 327.34
- EINECS:
- MDL Number:MFCD14585805
- Synonyms:5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine;LM-3319 FR 180204;FR 180204;1H-Pyrazolo[3,4-c]pyridazin-3-amine, 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-;5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine FR 180204;5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine;ERK Inhibitor II, FR180204;FR 180204, 98%, a potent and selective ATP-competitive inhibitor of ERK
4 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0320
- Product descriptionFR180204 ≥98% (HPLC)
- Packaging5MG
- Price₹16161.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0320
- Product descriptionFR180204 ≥98% (HPLC)
- Packaging25MG
- Price₹63964.93
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberF1214
- Product descriptionFR 180204
- Packaging25MG
- Price₹19800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberF1214
- Product descriptionFR 180204
- Packaging5MG
- Price₹7300
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0320 | FR180204 ≥98% (HPLC) | 5MG | ₹16161.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0320 | FR180204 ≥98% (HPLC) | 25MG | ₹63964.93 | 2022-06-14 | Buy |
TCI Chemicals (India) | F1214 | FR 180204 | 25MG | ₹19800 | 2022-05-26 | Buy |
TCI Chemicals (India) | F1214 | FR 180204 | 5MG | ₹7300 | 2022-05-26 | Buy |
Properties
Melting point :267 °C
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :7.19±0.50(Predicted)
form :Yellow solid
color :faint yellow to dark yellow
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :7.19±0.50(Predicted)
form :Yellow solid
color :faint yellow to dark yellow
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||
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Description
The extracellular regulated kinases 1 and 2 (ERK1/2) are functionally redundant kinases activated by a variety of growth factors and mitogens. FR180204 is a potent cell-permeable inhibitor of ERK1 and ERK2 (Ki = 310 and 140 nM, respectively). It is much less effective against p38α (IC50 = 10 μM) and does not inhibit a range of other serine/threonine or tyrosine kinases. FR180204 blocks ERK-mediated signaling from TGF-β to AP-1 (IC50 = 3.1 μM). It attenuates delayed-type hypersensitivity in collagen-immunized mice and ameliorates collagen-induced arthritis in mice.More related product prices
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Suppliers and manufacturers
career henan chemical co
TCI Chemicals (India) Pvt. Ltd.
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₹1.00 /1KG
5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine CAS:865362-74-9
5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine CAS:865362-74-9