SB 203580
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- ₹6500 - ₹37350
- Product name: SB 203580
- CAS: 152121-47-6
- MF: C21H16FN3OS
- MW: 377.43
- EINECS:
- MDL Number:MFCD00922198
- Synonyms:SB 203580 HYDROCHLORIDE;SB 2035850;4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL) 1H-IMIDAZOLE;4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL)1H-IMIDAZOLE, HCL;4-[5-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-3H-IMIDAZOL-4-YL]PYRIDINE;4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFONYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE;4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULPHONYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE HYDROCHLORIDE; 4-[5-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-4-yl]pyridine
6 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 10MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberF0864
- Product descriptionSB 203580
- Packaging25MG
- Price₹6500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberF0864
- Product descriptionSB 203580
- Packaging100MG
- Price₹14800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number559389
- Product descriptionSB 203580 - CAS 152121-47-6 - Calbiochem SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC??
- Packaging1MG
- Price₹20450
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS8307
- Product descriptionSB 203580 solid, ≥98% (HPLC)
- Packaging1MG
- Price₹24334.6
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number559389
- Product descriptionSB 203580 - CAS 152121-47-6 - Calbiochem SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC??
- Packaging5MG
- Price₹34100
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number559389
- Product descriptionSB 203580 - CAS 152121-47-6 - Calbiochem SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC??
- Packaging10MG
- Price₹37350
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | F0864 | SB 203580 | 25MG | ₹6500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | F0864 | SB 203580 | 100MG | ₹14800 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | 559389 | SB 203580 - CAS 152121-47-6 - Calbiochem SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC?? | 1MG | ₹20450 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S8307 | SB 203580 solid, ≥98% (HPLC) | 1MG | ₹24334.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 559389 | SB 203580 - CAS 152121-47-6 - Calbiochem SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC?? | 5MG | ₹34100 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 559389 | SB 203580 - CAS 152121-47-6 - Calbiochem SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC?? | 10MG | ₹37350 | 2022-06-14 | Buy |
Properties
Melting point :144-146
Boiling point :615.6±55.0 °C(Predicted)
Density :1.4
storage temp. :-20°C
solubility :DMSO: 50 mg/mL
form :solid
pka :9.60±0.10(Predicted)
color :white to off-white
Stability :-200C
InChIKey :CDMGBJANTYXAIV-UHFFFAOYSA-N
CAS DataBase Reference :152121-47-6(CAS DataBase Reference)
Boiling point :615.6±55.0 °C(Predicted)
Density :1.4
storage temp. :-20°C
solubility :DMSO: 50 mg/mL
form :solid
pka :9.60±0.10(Predicted)
color :white to off-white
Stability :-200C
InChIKey :CDMGBJANTYXAIV-UHFFFAOYSA-N
CAS DataBase Reference :152121-47-6(CAS DataBase Reference)
Safety Information
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Description
Mitogen-activated protein kinases (MAPK) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the expression of many cytokines, transcription factors, and cell surface receptors. SB 203580 is a pyridinyl imidazole inhibitor of p38 MAPK that specifically blocks its kinase activity. SB 203580 does not however, disrupt JNK activity, which is activated by similar stressors to those which activate p38 MAPK. p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580 with an IC50 value of 0.6 μM. SB 203580 also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1 (PDK1) at IC50 values of 3-5 μM.Related product price
- SB 203580 (hydrochloride)
₹15760-42220 - LY 294002 HYDROCHLORIDE
₹10660-37350 - PD 98059
₹6400-32230
