4'-CHLORO-3-METHOXYCINNAMANILIDE
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- ₹9400 - ₹65848.48
- Product name: 4'-CHLORO-3-METHOXYCINNAMANILIDE
- CAS: 472981-92-3
- MF: C16H14ClNO2
- MW: 287.74
- EINECS:
- MDL Number:MFCD01033818
- Synonyms:N-(3-METHOXYPHENYL)-4-CHLOROCINNAMIDE;SB 366791;4'-CHLORO-3-METHOXYCINNAMANILIDE;3-(4-Chlorophenyl)-N-(3-methoxyphenyl)-2-propenamide;(E)-3-(4-CHLOROPHENYL)-N-(3-METHOXYPHENYL)ACRYLAMIDE;2-Propenamide,3-(4-chlorophenyl)-N-(3-methoxyphenyl)-;SB 366791;SB366791;SB366791, >98%
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberB5762
- Product descriptionSB-366791 min. 98.0 %
- Packaging25MG
- Price₹9400
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberB5762
- Product descriptionSB-366791 min. 98.0 %
- Packaging100MG
- Price₹14800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS0441
- Product descriptionSB-366791 ≥98% (HPLC), powder
- Packaging5MG
- Price₹15260
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS0441
- Product descriptionSB-366791 ≥98% (HPLC), powder
- Packaging25MG
- Price₹65848.48
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | B5762 | SB-366791 min. 98.0 % | 25MG | ₹9400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B5762 | SB-366791 min. 98.0 % | 100MG | ₹14800 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | S0441 | SB-366791 ≥98% (HPLC), powder | 5MG | ₹15260 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S0441 | SB-366791 ≥98% (HPLC), powder | 25MG | ₹65848.48 | 2022-06-14 | Buy |
Properties
Melting point :165-167℃
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: 13 mg/mL, soluble
form :solid
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: 13 mg/mL, soluble
form :solid
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
The transient receptor potential vanilloid type 1 (TRPV1) receptor is a nonselective cation channel gated by noxious heat, protons, and capsaicin. TRPV1 is present in primary sensory neurons and in both central and peripheral sensory nerve terminals and plays a role in thermal and mechanical hyperalgesia. SB-366791 is a selective TRPV1 antagonist that is widely used in pain research. In cultured trigeminal ganglion neurons, SB-366791 inhibits capsaicin-evoked Ca2+ influx with an IC50 value of 0.7 μM. A 1 nmol injection of SB-366791 in mouse paw reduces capsaicin-induced nociceptive responses in a model of pain. Intrathecal pretreatment of 10 μl SB-366791 in rats suppresses tolerance to the analgesic effects of chronic morphine administration. Co-administration of morphine and SB-366791 at 0.1 mg/kg has potent analgesic effects in a mouse model of bone cancer pain.Related product price
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