SB216763
- ₹6800 - ₹63542.75
- Product name: SB216763
- CAS: 280744-09-4
- MF: C19H12Cl2N2O2
- MW: 371.22
- EINECS:
- MDL Number:MFCD09753369
- Synonyms:CS-332;GSK-3 Inhibitor IV, SB-216763 - CAS 280744-09-4 - Calbiochem;SB 216763;3-(2,4-DICHLOROPHENYL)-4-(1-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE;3-(2,4-Dichlorophenyl)-4-...;3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione;SB-216763(SB 216763);GSK-3 Inhibitor IV, SB-216763
5 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 25MG
- 50MG
- ManufacturerTCI Chemicals (India)
- Product numberB5716
- Product descriptionSB 216763
- Packaging10MG
- Price₹6800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberB5716
- Product descriptionSB 216763
- Packaging50MG
- Price₹14800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS3442
- Product descriptionSB 216763 >98% (HPLC)
- Packaging25MG
- Price₹63542.75
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number361566
- Product descriptionGSK-3 Inhibitor IV, SB-216763 - CAS 280744-09-4 - Calbiochem
- Packaging10MG
- Price₹17860
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS3442
- Product descriptionSB 216763 >98% (HPLC)
- Packaging5MG
- Price₹16475.65
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | B5716 | SB 216763 | 10MG | ₹6800 | 2022-05-26 | Buy |
TCI Chemicals (India) | B5716 | SB 216763 | 50MG | ₹14800 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | S3442 | SB 216763 >98% (HPLC) | 25MG | ₹63542.75 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 361566 | GSK-3 Inhibitor IV, SB-216763 - CAS 280744-09-4 - Calbiochem | 10MG | ₹17860 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | S3442 | SB 216763 >98% (HPLC) | 5MG | ₹16475.65 | 2022-06-14 | Buy |
Properties
Melting point :287-288.6 °C(lit.)
Boiling point :598.1±50.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: 20 mg/mL, soluble
form :Orange solid
pka :7.27±0.60(Predicted)
color :orange
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Boiling point :598.1±50.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: 20 mg/mL, soluble
form :Orange solid
pka :7.27±0.60(Predicted)
color :orange
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
SB 216763 is a cell-permeable, potent, selective and ATP-competitive inhibitor of GSK-3 (Glycogen Synthase Kinase) with an IC50 value of 34 nM for GSK-3α and with similar potency for GSK-3β. In PC-12 cells, SB-216763 exhibits neuroprotective properties and protects cultured central and peripheral nervous system neurones from cell death. Furthermore, SB-216763 increases the concentration of cytoplasmic β-catenin through a GSK-3 dependent manner. These inhibitory effects are similar to those of Wnt.More related product prices
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