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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Apoptosis >Caspase inhibitors >Z-VAD-FMK

Z-VAD-FMK

Z-VAD-FMK Structure
  • ₹32810 - ₹87628.38
  • Product name: Z-VAD-FMK
  • CAS: 187389-52-2
  • MF: C22H30FN3O7
  • MW: 467.49
  • EINECS:
  • MDL Number:MFCD03452883
  • Synonyms:Z-VADC(OME)-FMK;methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-phenylmethoxycarbonylamino-butanoyl]amino]propanoyl]amino]-4-oxo-pentanoate;N-BENZYLOXYCARBONYL-VAL-ALA-ASP FLUOROMETHYL KETONE;Z-VAD-FLUOROMETHYLKETONE;Z-VAD-FMK;Z-VAD-FMK, METHYL ESTER;Z-VAD(OME)-FLUOROMETHYLKETONE;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 2MG
  • 100μG
  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number627610
  • Product descriptionCaspase Inhibitor I - CAS 187389-52-2 - Calbiochem Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor.
  • Packaging1MG
  • Price₹32810
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number627610
  • Product descriptionCaspase Inhibitor I - CAS 187389-52-2 - Calbiochem Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor.
  • Packaging5MG
  • Price₹57700
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberV116
  • Product descriptionZ-VAD-FMK solid
  • Packaging2MG
  • Price₹87628.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSAB2501669
  • Product descriptionAnti-CASP3 antibody produced in goat affinity isolated antibody, buffered aqueous solution
  • Packaging100μG
  • Price₹53135.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 627610 Caspase Inhibitor I - CAS 187389-52-2 - Calbiochem Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor. 1MG ₹32810 2022-06-14 Buy
Sigma-Aldrich(India) 627610 Caspase Inhibitor I - CAS 187389-52-2 - Calbiochem Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor. 5MG ₹57700 2022-06-14 Buy
Sigma-Aldrich(India) V116 Z-VAD-FMK solid 2MG ₹87628.38 2022-06-14 Buy
Sigma-Aldrich(India) SAB2501669 Anti-CASP3 antibody produced in goat affinity isolated antibody, buffered aqueous solution 100μG ₹53135.7 2022-06-14 Buy

Properties

Melting point :>190°C (dec.)
Boiling point :732.4±60.0 °C(Predicted)
Density :1.214±0.06 g/cm3 (20 ºC 760 Torr)
Flash point :396.7℃
storage temp. :-20°C
solubility :DMSO: 20 mg/mL
form :powder
pka :11.05±0.46(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey :MIFGOLAMNLSLGH-QOKNQOGYSA-N
SMILES :C(N)(=O)[C@H](C)N(C(=O)[C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)[C@@H](CC(OC)=O)C(=O)CF
CAS DataBase Reference :187389-52-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases. Through this action, it inhibits cleavage of poly(ADP-ribose) polymerase, preventing apoptosis when used at 10-50 μM. It also blocks caspase-mediated apoptosis in vivo. Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes.

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Suppliers and manufacturers

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Z-VAD-FMK
₹1.00 /1KG
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