Z-VAD-FMK
- ₹32810 - ₹87628.38
- Product name: Z-VAD-FMK
- CAS: 187389-52-2
- MF: C22H30FN3O7
- MW: 467.49
- EINECS:
- MDL Number:MFCD03452883
- Synonyms:Z-VADC(OME)-FMK;methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-phenylmethoxycarbonylamino-butanoyl]amino]propanoyl]amino]-4-oxo-pentanoate;N-BENZYLOXYCARBONYL-VAL-ALA-ASP FLUOROMETHYL KETONE;Z-VAD-FLUOROMETHYLKETONE;Z-VAD-FMK;Z-VAD-FMK, METHYL ESTER;Z-VAD(OME)-FLUOROMETHYLKETONE;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-
4 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 2MG
- 5MG
- 1MG
- 100μG
- ManufacturerSigma-Aldrich(India)
- Product number627610
- Product descriptionCaspase Inhibitor I - CAS 187389-52-2 - Calbiochem Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor.
- Packaging1MG
- Price₹32810
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSAB2501669
- Product descriptionAnti-CASP3 antibody produced in goat affinity isolated antibody, buffered aqueous solution
- Packaging100μG
- Price₹53135.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number627610
- Product descriptionCaspase Inhibitor I - CAS 187389-52-2 - Calbiochem Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor.
- Packaging5MG
- Price₹57700
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberV116
- Product descriptionZ-VAD-FMK solid
- Packaging2MG
- Price₹87628.38
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 627610 | Caspase Inhibitor I - CAS 187389-52-2 - Calbiochem Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor. | 1MG | ₹32810 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SAB2501669 | Anti-CASP3 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 100μG | ₹53135.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 627610 | Caspase Inhibitor I - CAS 187389-52-2 - Calbiochem Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor. | 5MG | ₹57700 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | V116 | Z-VAD-FMK solid | 2MG | ₹87628.38 | 2022-06-14 | Buy |
Properties
Melting point :>190°C (dec.)
Boiling point :732.4±60.0 °C(Predicted)
Density :1.214±0.06 g/cm3 (20 ºC 760 Torr)
Flash point :396.7℃
storage temp. :-20°C
solubility :DMSO: 20 mg/mL
form :powder
pka :11.05±0.46(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey :MIFGOLAMNLSLGH-QOKNQOGYSA-N
SMILES :C(N)(=O)[C@H](C)N(C(=O)[C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)[C@@H](CC(OC)=O)C(=O)CF
CAS DataBase Reference :187389-52-2
Boiling point :732.4±60.0 °C(Predicted)
Density :1.214±0.06 g/cm3 (20 ºC 760 Torr)
Flash point :396.7℃
storage temp. :-20°C
solubility :DMSO: 20 mg/mL
form :powder
pka :11.05±0.46(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey :MIFGOLAMNLSLGH-QOKNQOGYSA-N
SMILES :C(N)(=O)[C@H](C)N(C(=O)[C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)[C@@H](CC(OC)=O)C(=O)CF
CAS DataBase Reference :187389-52-2
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases. Through this action, it inhibits cleavage of poly(ADP-ribose) polymerase, preventing apoptosis when used at 10-50 μM. It also blocks caspase-mediated apoptosis in vivo. Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes.More related product prices
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