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AC-LEU-GLU-THR-ASP-AFC

AC-LEU-GLU-THR-ASP-AFC Structure
  • ₹0
  • Product name: AC-LEU-GLU-THR-ASP-AFC
  • CAS: 210345-02-1
  • MF: C31H38F3N5O12
  • MW: 729.65
  • EINECS:
  • MDL Number:MFCD07780890
  • Synonyms:AC-LEU-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;AC-LEU-GLU-THR-ASP-AFC;AC-LETD-AFC;N-ACETYL-LEU-GLU-THR-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-Acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine;L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI);L-α-Asparagine,N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-;4-[(2-acetamido-4-methylpentanoyl)amino]-5-[[1-[[3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoicacid
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Properties

storage temp. :−20°C
solubility :DMSO: 10 mg/ml
form :White to off-white powder.

Safety Information

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Description

Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.

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