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ChemicalBook > Product Catalogue >Biochemical Engineering >Polypeptide >AC-DEVD-AFC

AC-DEVD-AFC

AC-DEVD-AFC Structure
  • ₹17731.35
  • Product name: AC-DEVD-AFC
  • CAS: 201608-14-2
  • MF: C30H34F3N5O13
  • MW: 729.61
  • EINECS:
  • MDL Number:MFCD01310970
  • Synonyms:N-ACETYL-ASP-GLU-VAL-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-ACETYL-ASP-GLU-VAL-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN);N-ACETYL-ASP-GLU-VAL-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC;CASPASE 3 (APOPAIN) SUBSTRATE 1F, FLUOROGENIC;CASPASE-3 SUBSTRATE (AFC);CASPASE-3 SUBSTRATE VII, FLUOROGENIC;CASPASE-3 FLUOROGENIC SUBSTRATE;FLUOROGENIC CASPASE 3 SUBSTRATE AC-DEVD-AFC
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberA0466
  • Product descriptionN-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin ≥90% (HPLC), powder
  • Packaging1MG
  • Price₹17731.35
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A0466 N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin ≥90% (HPLC), powder 1MG ₹17731.35 2022-06-14 Buy

Properties

Boiling point :1152.7±65.0 °C(Predicted)
Density :1.495±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :H2O: 1 mg/mL
form :powder
pka :4.09±0.10(Predicted)
color :white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 μM), as well as related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.

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