Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE
- ₹0
- Product name: Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE
- CAS: 153088-73-4
- MF: C20H17Cl2NO7
- MW: 454.26
- EINECS:
- MDL Number:MFCD00674885
- Synonyms:N-cbz-L-aspartic acid A-(2,6-dichloro-*benzoyloxy;N-CBZ-L-ASPARTIC ACID A-(2 6-DICHLORO- &;INTERLEUKIN-1BETA CONVERTING ENZYME INHIBITOR III;N-CBZ-L-aspartic acid alpha-[(2,6-dichlorobenzoyloxy)....;Z-L-Asp α-([2,6-dichlorobenzoyloxy]methyl ketone);CASPASE-1 INHIBITOR V ;Z-VAL-ALA-ASP(OME)-FLUOROMETHYLKETONE;ICE INHIBITOR V;ICE INHIBITOR VI
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Properties
Boiling point :674.2±55.0 °C(Predicted)
Density :1.440±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :White to off-white powder.
pka :4.01±0.19(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Density :1.440±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :White to off-white powder.
pka :4.01±0.19(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Description
Z-Asp-CH2-DCB is a peptide originally synthesized for its ability to inactivate the interleukin-1β-converting enzyme, which is the homolog of the C. elegans positive regulator of apoptosis CED-3. Z-Asp-CH2-DCB has been shown to block apoptosis by nonselectively inhibiting caspase activity. At 1-100 μM, it can dose-dependently block the production of IL-1β, TNF-α, IL-6, and IFN-γ by human peripheral blood mononuclear cells as well as inhibit T cell proliferation.Related product price
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