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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Aspartic acid derivatives >AC-VEID-AMC

AC-VEID-AMC

AC-VEID-AMC Structure
  • ₹0
  • Product name: AC-VEID-AMC
  • CAS: 219137-97-0
  • MF: C32H43N5O11
  • MW: 673.71
  • EINECS:
  • MDL Number:MFCD01318831
  • Synonyms:N-ACETYL-VAL-GLU-ILE-ASP-7-AMINO-4-METHYLCOUMARIN AMC;CASPASE-6 SUBSTRATE (FLUOROGENIC);CASPASE-6 SUBSTRATE I, FLUOROGENIC;CASPASE 6 (MCH2) SUBSTRATE 1M, FLUOROGENIC;ACETYL-L-VALYL-L-GLUTAMYL-L-ISOLEUCYL-L-ASPARTIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE);AC-VEID-MCA;AC-VEID-AMC;AC-VAL-GLU-ILE-ASP-7-AMINO-4-METHYLCOUMARIN
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :1106.8±65.0 °C(Predicted)
Density :1.311±0.06 g/cm3(Predicted)
storage temp. :−20°C
form :powder
pka :4.09±0.10(Predicted)
color :white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis. It has also been reported to be cleaved by related proteases, including caspase-8. Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.

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