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Z-Vad-fmk, non-methylated

Z-Vad-fmk, non-methylated Structure
  • ₹10670 - ₹31630.01
  • Product name: Z-Vad-fmk, non-methylated
  • CAS: 161401-82-7
  • MF: C21H28FN3O7
  • MW: 453.46
  • EINECS:
  • MDL Number:
  • Synonyms:Z-VAL-ALA-ASP-(OH)-FLUOROMETHYL KETONE;Z-VAD-FMK (Caspase Inhibitor VI);Carbobenzyloxy-Val-Ala-Asp-alpha-fluoromethylketone;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]- (9ci);L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-, (S)-;Z-VAD-FMK, Free Acid;Z-VAD(OH)-FMK (Caspase Inhibitor VI)
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 250μG
  • ManufacturerSigma-Aldrich(India)
  • Product number219007
  • Product descriptionCaspase Inhibitor VI - CAS 161401-82-7 - Calbiochem Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
  • Packaging250μG
  • Price₹10670
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number219007
  • Product descriptionCaspase Inhibitor VI - CAS 161401-82-7 - Calbiochem Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
  • Packaging1MG
  • Price₹31630.01
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 219007 Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies. 250μG ₹10670 2022-06-14 Buy
Sigma-Aldrich(India) 219007 Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies. 1MG ₹31630.01 2022-06-14 Buy

Properties

Boiling point :758.0±60.0 °C(Predicted)
Density :1.260±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO:5.0(Max Conc. mg/mL);11.0(Max Conc. mM)
pka :3.91±0.19(Predicted)
form :Off-white solid
color :White to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Z-VAD(OH)-FMK is an irreversible tripeptide inhibitor of all caspases. This non-methylated form is useful in studies involving recombinant, isolated, or purified enzymes. Unlike the methylated form, Z-VAD(OMe)-FMK , this compound does not require pretreatment with esterases prior to in vitro use.

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