WIN 55,212-2 MESYLATE
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- ₹47565.05 - ₹91363
- Product name: WIN 55,212-2 MESYLATE
- CAS: 131543-23-2
- MF: C28H30N2O6S
- MW: 522.62
- EINECS:1592732-453-0
- MDL Number:MFCD00153882
- Synonyms:R(+)-WIN 55,212-2 ,MESYLATE HIGH AFFINIT Y CANNABI;(R)-(+)-(2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1.2.3-de]-1,4-benzoxazin-6-yl)-1-naphthalenylmethanonemesy;212-2Mesylate;WIN55;(R)-(+)-[2,3-Dihydro-5-methyl-3[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate salt;(R)-(+)-WIN 55,212-2 mesylate salt;WIN 552122 mesylate, (R)-(+)-[2,3-Dihydro-5-methyl-3[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate salt;(R)-(5-Methyl-3-(MorpholinoMethyl)-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indol-6-yl)(naphthalen-1-yl)Methanone
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 25MG
- 100MG
- ManufacturerSigma-Aldrich(India)
- Product numberW102
- Product description(R)-(+)-WIN 55,212-2 mesylate salt ≥98% (HPLC)
- Packaging25MG
- Price₹47565.05
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberW102
- Product description(R)-(+)-WIN 55,212-2 mesylate salt ≥98% (HPLC)
- Packaging100MG
- Price₹91363
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | W102 | (R)-(+)-WIN 55,212-2 mesylate salt ≥98% (HPLC) | 25MG | ₹47565.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W102 | (R)-(+)-WIN 55,212-2 mesylate salt ≥98% (HPLC) | 100MG | ₹91363 | 2022-06-14 | Buy |
Properties
storage temp. :Store at +4°C
solubility :0.1 M HCl: 0.25 mg/mL
form :solid
color :white to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :FSGCSTPOPBJYSX-OZYVVJTJNA-N
SMILES :S(O)(=O)(=O)C.C(N1CCOCC1)[C@@H]1COC2=CC=CC3C(C(C4=CC=CC5=CC=CC=C45)=O)=C(C)N1C=32 |&1:12,r|
solubility :0.1 M HCl: 0.25 mg/mL
form :solid
color :white to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :FSGCSTPOPBJYSX-OZYVVJTJNA-N
SMILES :S(O)(=O)(=O)C.C(N1CCOCC1)[C@@H]1COC2=CC=CC3C(C(C4=CC=CC5=CC=CC=C45)=O)=C(C)N1C=32 |&1:12,r|
Safety Information
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Description
(+)-WIN 55,212-2 (mesylate) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Ki values of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. In primary cultures of rat cerebral cortex neurons, (+)-WIN 55,212-2 (mesylate) (0.01-100 nM) increases extracellular glutamate levels, displaying a bell-shaped concentration-response curve. This effect is fully counteracted by rimonabant at a concentration of 10 nM, by decreasing Ca2+ concentrations below 0.2 mM, or by the IP3 receptor antagonist xestospongin C at a concentration of 1 μM. (+)-WIN 55,212-2 (mesylate) induces release of the proinflammatory neuropeptide CGRP from trigeminal ganglion (TG) neurons in a calcium-dependent manner with an EC50 value of 26 μM.Related product price
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