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CAFESTOL

CAFESTOL Structure
  • ₹32341 - ₹54237
  • Product name: CAFESTOL
  • CAS: 469-83-0
  • MF: C20H28O3
  • MW: 316.43
  • EINECS:
  • MDL Number:MFCD01075769
  • Synonyms:CAFESTEROL;CAFESTOL;3bα,4,5,6,7,8,9,10,10aα,10b,11,12-Dodecahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7α-methanol;5A,8-Methano-5ah-cyclohepta(5,6)naphtho(2,1-B)furan-7-methanol, 3B,4,5,6,7,8,9,10,10A,10B,11,12-dodecahydro-7-hydroxy-10B-methyl-, (3bs-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta))-;5A,8-Methano-5ah-cyclohepta(5,6)naphtho(2,1-B)furan-7-methanol, 3B,4,5,6,7,8,9,10,10A,10B,11,12-dodecahydro-7-hydroxy-10B-methyl-, (3bs,5as,7R,8R,10ar,10bs)-;Ccris 1518;CAFESTOL(SH);(3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
Price2 Properties Safety Information Description
2 prices
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Brand

  • ALFA India

Package

  • 50mg
  • 100mg
  • ManufacturerALFA India
  • Product numberALF-J65355-MF
  • Product descriptionCafestol
  • Packaging50mg
  • Price₹32341
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J65355-MC
  • Product descriptionCafestol
  • Packaging100mg
  • Price₹54237
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J65355-MF Cafestol 50mg ₹32341 2022-05-26 Buy
ALFA India ALF-J65355-MC Cafestol 100mg ₹54237 2022-05-26 Buy

Properties

Melting point :160-162℃ (Decomposition) (ethyl ether pentane )
alpha :D -101°
Boiling point :468.6±45.0 °C(Predicted)
Density :1.23±0.1 g/cm3 (20 ºC 760 Torr)
RTECS :PB9185090
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Soluble in dichlormethane, DMSO or ethanol
pka :14.44±0.40(Predicted)
form :White to off-white solid.
color :Off-White to Light Beige
optical activity :-9724 (CHCl3)
LogP :4.234 (est)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cafestol is a natural diterpene which is abundant in unfiltered coffee. It elevates serum cholesterol and triglycerides in humans, an effect which does not seem to occur in monkeys, hamsters, rats, or gerbils. Dietary cafestol does increase total cholesterol and triglycerides in ApoE3Leiden mice, an effect which is associated with selective activation of farnesoid X receptors and pregnane X receptors. Cafestol (20 μM) also inhibits the proliferation of human umbilical vein endothelial cells and prevents their migration and tube formation on Matrigel?.

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