1-AZAKENPAULLONE
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- ₹6000 - ₹58054.48
- Product name: 1-AZAKENPAULLONE
- CAS: 676596-65-9
- MF: C15H10BrN3O
- MW: 328.16
- EINECS:200-258-5
- MDL Number:MFCD09037522
- Synonyms:1-AZAKENPAULLONE;9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one;Pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one, 9-broMo-7,12-dihydro-;InSolution? 1-Azakenpaullone ;1-Azakenpaullone 9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one;InSolution 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem;1-Azakenpaullone - CAS 676596-65-9 - Calbiochem;azakenpaullone
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 500μG
- ManufacturerSigma-Aldrich(India)
- Product number191501
- Product descriptionInSolution 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem A Kenpaullone analog that acts as a potent and ATP-competitive inhibitor of GSK-3&beta.
- Packaging500μG
- Price₹6000
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA3734
- Product description1-Azakenpaullone ≥97% (HPLC)
- Packaging1MG
- Price₹14516.33
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA3734
- Product description1-Azakenpaullone ≥97% (HPLC)
- Packaging5MG
- Price₹58054.48
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 191501 | InSolution 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem A Kenpaullone analog that acts as a potent and ATP-competitive inhibitor of GSK-3&beta. | 500μG | ₹6000 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A3734 | 1-Azakenpaullone ≥97% (HPLC) | 1MG | ₹14516.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A3734 | 1-Azakenpaullone ≥97% (HPLC) | 5MG | ₹58054.48 | 2022-06-14 | Buy |
Properties
Melting point :>290°C (dec.)
Boiling point :648.8±50.0 °C(Predicted)
Density :1.655±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :13.36±0.20(Predicted)
form :Tan solid
color :gray-brown
InChI :InChI=1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20)
InChIKey :NTSBZVCEIVPKBJ-UHFFFAOYSA-N
SMILES :N1C2=C(C=C(Br)C=C2)C2CC(=O)NC3=CC=CN=C3C1=2
Boiling point :648.8±50.0 °C(Predicted)
Density :1.655±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :13.36±0.20(Predicted)
form :Tan solid
color :gray-brown
InChI :InChI=1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20)
InChIKey :NTSBZVCEIVPKBJ-UHFFFAOYSA-N
SMILES :N1C2=C(C=C(Br)C=C2)C2CC(=O)NC3=CC=CN=C3C1=2
Safety Information
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Description
1-Azakenpaullone is an analog of kenpaullone that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 μM, respectively). Through its effects on GSK3β, 1-azakenpaullone stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells and Nematostella larvae.Related product price
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