AR-A014418
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- ₹16421.53 - ₹65675.28
- Product name: AR-A014418
- CAS: 487021-52-3
- MF: C12H12N4O4S
- MW: 308.31
- EINECS:
- MDL Number:MFCD08277040
- Synonyms:N-(4-Methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea AR 0133418;AR 0133418;GSK 3B Inhibitor VIII;AR 014418;GSK 3β inhibitor;1-(4-Methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea;AR-A014418/ARA014418;SN 4521
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberA3230
- Product descriptionAR-A014418 ≥98% (HPLC), solid
- Packaging5MG
- Price₹16421.53
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number361549
- Product descriptionGSK-3β Inhibitor VIII - CAS 487021-52-3 - Calbiochem The GSK-3β Inhibitor VIII, also referenced under CAS 487021-52-3, controls the biological activity of GSK-3β. This small molecule/inhibitor is primari
- Packaging5MG
- Price₹16670.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA3230
- Product descriptionAR-A014418 ≥98% (HPLC), solid
- Packaging25MG
- Price₹65675.28
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A3230 | AR-A014418 ≥98% (HPLC), solid | 5MG | ₹16421.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 361549 | GSK-3β Inhibitor VIII - CAS 487021-52-3 - Calbiochem The GSK-3β Inhibitor VIII, also referenced under CAS 487021-52-3, controls the biological activity of GSK-3β. This small molecule/inhibitor is primari | 5MG | ₹16670.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A3230 | AR-A014418 ≥98% (HPLC), solid | 25MG | ₹65675.28 | 2022-06-14 | Buy |
Properties
Melting point :208-210?C (dec.)
Density :1.464±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL, clear, light yellow
form :Yellow solid
pka :5.80±0.70(Predicted)
color :off-white to tan
Sensitive :Light Sensitive
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Density :1.464±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL, clear, light yellow
form :Yellow solid
pka :5.80±0.70(Predicted)
color :off-white to tan
Sensitive :Light Sensitive
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
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Description
GSK3β Inhibitor VIII is an ATP-competitive inhibitor of the serine/threonine kinase, glycogen synthase kinase 3β (Ki = 38 nM; IC50 = 104 nM). It does not significantly inhibit the closely related cyclin-dependent kinase (Cdk)2 or Cdk5 (Kis = > 100 μM). GSK3β Inhibitor VIII demonstrates neuroprotective effects by inhibiting tau phosphorylation (IC50 = 2.7 μM) at a GSK3-specific site (Ser396) in cells stably expressing human four-repeat tau protein and also by protecting β-amyloid-exposed N2A neuroblastoma cells against cell death.More related product prices
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