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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >PI3K / Akt / mTOR >GSK-3 inhibitors >SB 415286

SB 415286

SB 415286 Structure
  • ₹16260 - ₹58700
  • Product name: SB 415286
  • CAS: 264218-23-7
  • MF: C16H10ClN3O5
  • MW: 359.72
  • EINECS:
  • MDL Number:MFCD04039789
  • Synonyms:1H-Pyrrole-2,5-dione, 3-[(3-chloro-4-hydroxyphenyl)aMino]-4-(2-nitrophenyl)-;SB 415286;3-[(3-CHLORO-4-HYDROXYPHENYL)AMINO]-4-(2-NITROPHENYL)-1H-PYRROLE-2,5-DIONE;3-[(3-CHLORO-4-HYDROXYPHENYL)AMINO]-4-(2-NITROPHENYL)-1H-PYRROL-2,5-DIONE;7-L-Alanine-cyclosporin A;SB 415286 USP/EP/BP;SB-41528;CS-228
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberS3567
  • Product descriptionSB 415286 ≥98% (HPLC)
  • Packaging25MG
  • Price₹58700
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS3567
  • Product descriptionSB 415286 ≥98% (HPLC)
  • Packaging5MG
  • Price₹16260
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) S3567 SB 415286 ≥98% (HPLC) 25MG ₹58700 2022-06-14 Buy
Sigma-Aldrich(India) S3567 SB 415286 ≥98% (HPLC) 5MG ₹16260 2022-06-14 Buy

Properties

Boiling point :595.8±50.0 °C(Predicted)
Density :1.647
storage temp. :-20°C
solubility :DMSO: 16 mg/mL
form :Yellow Solid.
pka :6.81±0.60(Predicted)
color :yellow to orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SB-415286 is an ATP-competitive inhibitor of GSK3α (Glycogen Synthase Kinase 3α) with a Ki value of 31 nM. SB-415286 displays similar potency for GSK-3β. Alternate studies suggest that SB-415286 stabilizes β-catenin, which in turn leads to inhibition of coxsackievirus-induced cell death. SB-415286 is an inhibitor of GSK-3 β.

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Suppliers and manufacturers

career henan chemical co
SB 415286
₹1.00 /1g
SB 415286 CAS:264218-23-7
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